The GReD is a Research Center at Clermont-Ferrand, Auvergne Rhône Alpes region of France. Created in 2008, the GReD is supported by the University Clermont Auvergne (UCA), the CNRS (UMR6293) and the INSERM (U1103). The center is composed of 14 research groups (totalling 147 people in December 2017) based at the Centre de Recherche Bio-Clinique (CRBC) on the campus of the Faculty of Medecine.

The biological questions posed by the GReD research labs aim at understanding the genetic and epigenetic programs leading to development and reproduction, and how their deregulation can result in disease. The name of the center comes from these research themes: Genetics, Reproduction and Development


Our research concerns three major themes including 15 teams:

  1. Genome dynamics and epigenetic control:
  2. Reproduction and development in health and disease:
  3. Endocrinology, signaling and cancer:

The three research axes thus combine molecular and cellular biology, imaging and genetic screens. Working with multiple biological models (vertebrates, insects, plants) permits us to exploit the particular advantages of each for research and experimentation. Our research work, and notably the study of human genetic diseases including cancer, has great technology transfer potential for clinical applications - in line with our strategic scientific policy aiming to strengthen the continuum between basic and clinical research. 

The strengths of the Unit:

  • Complementarity of technical approaches and models.
  • Coordination and sharing of cutting-edge technical facilities.
  • High potential for the transfer of technology to clinical applications, in keeping with the marketing policy.
  • Significant training activities within universities in Clermont-Ferrand.

Research thematics