Matthieu JABAUDON

M.D., Ph.D.

Resume

Matthieu JABAUDONprofile picture

Professor of Anesthesiology, Critical Care, and Perioperative Medicine

Department of Anesthesiology, Critical Care, and Perioperative Medicine, CHU Clermont-Ferrand
Team « Translational Approach to epithelial injury and repair”, iGReD, Universite Clermont Auvergne, CNRS, INSERM
58 rue Montalembert, 63000 Clermont-Ferrand, France
Email: mjabaudon@chu.clermontferrand.fr

Education
MD in Anesthesiology, Critical Care, and Perioperative Medicine - CHU Clermont-Ferrand, Université Clermont Auvergne (2008)
PhD in Biological Sciences - Université Clermont Auvergne, GReD, CNRS, INSERM (2016)

Postgraduate Training
Visiting Associate Professor of Medicine, Vanderbilt University Medical Center (2019-2020)

Research

Research Keywords

Translational research in acute lung injury and repair; Acute respiratory distress syndrome; Mechanical ventilation; Inhaled anesthetics; Biomarkers; Personalized Medicine.

Research Description

Our Hospital research team and University lab do basic, translational and clinical research on the role of the alveolar epithelium in the pathogenesis and resolution of acute lung injury and the acute respiratory distress syndrome (ARDS). Current projects include studies of the effects of inhaled anesthetics (sevoflurane, isoflurane) in acute lung injury and repair, investigation of the role of the receptor for advanced glycation end-products (RAGE) pathway and of the alveolar epithelium in the pathogenesis and resolution of acute lung injury, and translational studies of biomarkers for diagnosis and prognosis in acute lung injury

Publications

View Publications in PubMed

ORCID

0000-0002-8121-1680

Twitter

@mj0b

Publications

  • 2020
  • 2019
  • 2018
    • C. Egron, L. Roszyk, E. Rochette, M. Jabaudon, V. Sapin, A. Mulliez, A. Labbe and K. Coste, “Serum soluble receptor for advanced glycation end-products during acute bronchiolitis in infant: Prospective study in 93 cases.”, Pediatric pulmonology, vol. 53 (10) , pp. 1429–1435, 2018.
    • R. Blondonnet, B. Paquette, D. Richard, R. Bourg, G. Laplace, R. Segurel, H. Pouvelle, C. Belville, L. Blanchon, T. Godet, J. Constantin, J. Bazin, V. Sapin and M. Jabaudon, “In Vitro Method to Control Concentrations of Halogenated Gases in Cultured Alveolar Epithelial Cells.”, Journal of visualized experiments : JoVE, 2018.
    • M. Jabaudon, R. Blondonnet, B. Pereira, R. Cartin-Ceba, C. Lichtenstern, T. Mauri, R. Determann, T. Drabek, R. Hubmayr, O. Gajic, F. Uhle, A. Coppadoro, A. Pesenti, M. Schultz, M. Ranieri, H. Brodska, S. Mrozek, V. Sapin, M. Matthay, J. Constantin and C. Calfee, “Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data.”, Intensive care medicine, vol. 44 (9) , pp. 1388–1399, 2018.
    • R. Blondonnet, E. Joubert, T. Godet, P. Berthelin, T. Pranal, L. Roszyk, R. Chabanne, N. Eisenmann, A. Lautrette, C. Belville, S. Cayot, T. Gillart, B. Souweine, D. Bouvier, L. Blanchon, V. Sapin, B. Pereira, J. Constantin and M. Jabaudon, “Driving pressure and acute respiratory distress syndrome in critically ill patients.”, Respirology (Carlton, Vic.), 2018.
    • J. Constantin, T. Godet and M. Jabaudon, “Understanding Macrophages in Acute Respiratory Distress Syndrome: From Pathophysiology to Precision Medicine.”, Critical care medicine, vol. 46 (7) , pp. 1207–1208, 2018.
    • M. Jabaudon, R. Blondonnet, J. Audard, M. Fournet, T. Godet, V. Sapin and J. Constantin, “Recent directions in personalised acute respiratory distress syndrome medicine.”, Anaesthesia, critical care & pain medicine, vol. 37 (3) , pp. 251–258, 2018.
    • M. Jabaudon, R. Blondonnet and J. Constantin, “Distinct Biological Effects of Time-Controlled Adaptive Ventilation in Pulmonary and Extrapulmonary Acute Respiratory Distress Syndrome: "One Small Step for Rats, One Giant Leap for Humans?"”, Critical care medicine, vol. 46 (6) , pp. 1038–1040, 2018.
    • R. Blondonnet, T. Godet, E. Futier, J. Bazin, J. Constantin and M. Jabaudon, “Reply to Riche et al.: Sevoflurane in Acute Respiratory Distress Syndrome: Are Lung Protection and Anesthesia Depth Influenced by Pulmonary Morphology?”, American journal of respiratory and critical care medicine, vol. 197 (6) , pp. 832–834, 2018.
    • M. Jabaudon, P. Berthelin, T. Pranal, L. Roszyk, T. Godet, J. Faure, R. Chabanne, N. Eisenmann, A. Lautrette, C. Belville, R. Blondonnet, S. Cayot, T. Gillart, J. Pascal, Y. Skrzypczak, B. Souweine, L. Blanchon, V. Sapin, B. Pereira and J. Constantin, “Receptor for advanced glycation end-products and ARDS prediction: a multicentre observational study.”, Scientific reports, vol. 8 (1) , pp. 2603, 2018.
    • T. Godet, M. Jabaudon, R. Blondonnet, A. Tremblay, J. Audard, B. Rieu, B. Pereira, J. Garcier, E. Futier and J. Constantin, “High frequency percussive ventilation increases alveolar recruitment in early acute respiratory distress syndrome: an experimental, physiological and CT scan study.”, Critical care (London, England), vol. 22 (1) , pp. 3, 2018.
    • T. Pranal, B. Pereira, P. Berthelin, L. Roszyk, T. Godet, R. Chabanne, N. Eisenmann, A. Lautrette, C. Belville, R. Blondonnet, S. Cayot, T. Gillart, Y. Skrzypczak, B. Souweine, D. Bouvier, L. Blanchon, V. Sapin, J. Constantin and M. Jabaudon, “Clinical and Biological Predictors of Plasma Levels of Soluble RAGE in Critically Ill Patients: Secondary Analysis of a Prospective Multicenter Observational Study.”, Disease markers, vol. 2018 , pp. 7849675, 2018.
  • 2017
  • 2016
    • S. Mrozek, M. Jabaudon, S. Jaber, C. Paugam-Burtz, J. Lefrant, J. Rouby, K. Asehnoune, B. Allaouchiche, O. Baldesi, M. Leone, Q. Lu, J. Bazin, L. Roszyk, V. Sapin, E. Futier, B. Pereira and J. Constantin, “Elevated Plasma Levels of sRAGE Are Associated With Nonfocal CT-Based Lung Imaging in Patients With ARDS: A Prospective Multicenter Study.”, Chest, vol. 150 (5) , pp. 998–1007, 2016.
    • D. Bouvier, T. Duret, P. Rouzaire, M. Jabaudon, M. Rouzaire, C. Nourrisson, C. Bourgne, B. Pereira, B. Evrard and V. Sapin, “Preanalytical, analytical, gestational and pediatric aspects of the S100B immuno-assays.”, Clinical chemistry and laboratory medicine, vol. 54 (5) , pp. 833–42, 2016.
    • M. Jabaudon, R. Blondonnet, J. Lutz, L. Roszyk, D. Bouvier, R. Guerin, S. Perbet, S. Cayot, T. Godet, L. Blanchon, J. Bazin, E. Futier, V. Sapin and J. Constantin, “Net alveolar fluid clearance is associated with lung morphology phenotypes in acute respiratory distress syndrome.”, Anaesthesia, critical care & pain medicine, vol. 35 (2) , pp. 81–6, 2016.
    • R. Blondonnet, J. Constantin, V. Sapin and M. Jabaudon, “A Pathophysiologic Approach to Biomarkers in Acute Respiratory Distress Syndrome.”, Disease markers, vol. 2016 , pp. 3501373, 2016.
  • 2015
    • M. Jabaudon, E. Futier, L. Roszyk, V. Sapin, B. Pereira and J. Constantin, “Association between intraoperative ventilator settings and plasma levels of soluble receptor for advanced glycation end-products in patients without pre-existing lung injury.”, Respirology (Carlton, Vic.), vol. 20 (7) , pp. 1131–8, 2015.
    • M. Jabaudon, R. Blondonnet, L. Roszyk, D. Bouvier, J. Audard, G. Clairefond, M. Fournier, G. Marceau, P. Dechelotte, B. Pereira, V. Sapin and J. Constantin, “Soluble Receptor for Advanced Glycation End-Products Predicts Impaired Alveolar Fluid Clearance in Acute Respiratory Distress Syndrome.”, American journal of respiratory and critical care medicine, vol. 192 (2) , pp. 191–9, 2015.
    • M. Jabaudon, N. Hamroun, L. Roszyk, R. Guerin, J. Bazin, V. Sapin, B. Pereira and J. Constantin, “Effects of a recruitment maneuver on plasma levels of soluble RAGE in patients with diffuse acute respiratory distress syndrome: a prospective randomized crossover study.”, Intensive care medicine, vol. 41 (5) , pp. 846–55, 2015.
    • M. Jabaudon, R. Blondonnet, L. Roszyk, B. Pereira, R. Guerin, S. Perbet, S. Cayot, D. Bouvier, L. Blanchon, V. Sapin and J. Constantin, “Soluble Forms and Ligands of the Receptor for Advanced Glycation End-Products in Patients with Acute Respiratory Distress Syndrome: An Observational Prospective Study.”, PLoS ONE, vol. 10 (8) , pp. e0135857, 2015.
  • 2013
    • M. Jabaudon, S. Perbet, B. Pereira, A. Soummer, L. Roszyk, R. Guerin, E. Futier, Q. Lu, J. Bazin, V. Sapin, J. Rouby and J. Constantin, “Plasma levels of sRAGE, loss of aeration and weaning failure in ICU patients: a prospective observational multicenter study.”, PLoS ONE, vol. 8 (5) , pp. e64083, 2013.