Directeur de recherche CNRS


Olivier MATHIEUprofile picture
ORCID iD icon https://orcid.org/0000-0001-5302-1102
  • 2014. EMBO Young Investigator Award
  • 2012. Bronze Medal of the CNRS
  • 2011. Honorary Diploma of University Blaise Pascal
  • 2010. European Research Council Starting Grant




  • 2022
    • O. Mathieu, “Reaching the inaccessible DNA.”, Nat. Rev. Mol. Cell Biol., 2022.
  • 2021
    • A. Schmucker, B. Lei, Z. Lorkovic, M. Capella, S. Braun, P. Bourguet, O. Mathieu, K. Mechtler and F. Berger, “Crosstalk between H2A variant-specific modifications impacts vital cell functions.”, PLoS Genet., vol. 17 (6) , pp. e1009601, 2021.
    • P. Bourguet, C. Picard, R. Yelagandula, T. Pelissier, Z. Lorkovic, S. Feng, M. Pouch-Pelissier, A. Schmucker, S. Jacobsen, F. Berger and O. Mathieu, “The histone variant H2A.W and linker histone H1 co-regulate heterochromatin accessibility and DNA methylation.”, Nature communications, vol. 12 (1) , pp. 2683, 2021.
  • 2020
  • 2019
    • C. Luxan-Hernandez, J. Lohmann, W. Hellmeyer, S. Seanpong, K. Woltje, Z. Magyar, A. Pettko-Szandtner, T. Pelissier, G. De Jaeger, S. Hoth, O. Mathieu and M. Weingartner, “PP7L is essential for MAIL1-mediated TE silencing and primary root growth.”, Plant J., 2019.
  • 2018
    • P. Bourguet, S. de Bossoreille, L. Lopez-Gonzalez, M. Pouch-Pelissier, A. Gomez-Zambrano, A. Devert, T. Pelissier, R. Pogorelcnik, I. Vaillant and O. Mathieu, “A role for MED14 and UVH6 in heterochromatin transcription upon destabilization of silencing.”, Life science alliance, vol. 1 (6) , pp. e201800197, 2018.
    • Y. Ikeda, R. Nishihama, S. Yamaoka, M. Arteaga-Vazquez, A. Aguilar-Cruz, D. Grimanelli, R. Pogorelcnik, R. Martienssen, K. Yamato, T. Kohchi, T. Hirayama and O. Mathieu, “Loss of CG methylation in Marchantia polymorpha causes disorganization of cell division and reveals unique DNA methylation regulatory mechanisms of non-CG methylation.”, Plant & cell physiology, 2018.
  • 2017
  • 2016
  • 2014
    • O. Mathieu and N. Bouche, “Interplay between chromatin and RNA processing.”, Curr. Opin. Plant Biol., vol. 18C , pp. 60–65, 2014.
  • 2012
    • M. Rigal, Z. Kevei, T. Pelissier and O. Mathieu, “DNA methylation in an intron of the IBM1 histone demethylase gene stabilizes chromatin modification patterns.”, EMBO J., vol. 31 (13) , pp. 2981–93, 2012.
    • T. Pélissier and O. Mathieu, “Glue for Jumping Elements: Epigenetic Means for Controlling Transposable Elements in Plants”, Plant Transposable Elements, pp. 125–145, 2012.
  • 2011
    • M. Rigal and O. Mathieu, “A "mille-feuille" of silencing: epigenetic control of transposable elements.”, Biochim. Biophys. Acta, vol. 1809 (8) , pp. 452–8, 2011.
  • 2010
    • M. Tittel-Elmer, E. Bucher, L. Broger, O. Mathieu, J. Paszkowski and I. Vaillant, “Stress-induced activation of heterochromatic transcription.”, PLoS Genet., vol. 6 (10) , pp. e1001175, 2010.
  • 2009
    • S. Tsukahara, A. Kobayashi, A. Kawabe, O. Mathieu, A. Miura and T. Kakutani, “Bursts of retrotransposition reproduced in Arabidopsis.”, Nature, vol. 461 (7262) , pp. 423–6, 2009.
    • M. Mirouze, J. Reinders, E. Bucher, T. Nishimura, K. Schneeberger, S. Ossowski, J. Cao, D. Weigel, J. Paszkowski and O. Mathieu, “Selective epigenetic control of retrotransposition in Arabidopsis.”, Nature, vol. 461 (7262) , pp. 427–30, 2009.
  • 2008
    • M. Caikovski, C. Yokthongwattana, Y. Habu, T. Nishimura, O. Mathieu and J. Paszkowski, “Divergent evolution of CHD3 proteins resulted in MOM1 refining epigenetic control in vascular plants.”, PLoS Genet., vol. 4 (8) , pp. e1000165, 2008.
  • 2007
    • O. Mathieu, J. Reinders, M. Caikovski, C. Smathajitt and J. Paszkowski, “Transgenerational stability of the Arabidopsis epigenome is coordinated by CG methylation.”, Cell, vol. 130 (5) , pp. 851–62, 2007.
  • 2006
    • Y. Habu, O. Mathieu, M. Tariq, A. Probst, C. Smathajitt, T. Zhu and J. Paszkowski, “Epigenetic regulation of transcription in intermediate heterochromatin.”, EMBO Rep., vol. 7 (12) , pp. 1279–84, 2006.
    • I. Vaillant, I. Schubert, S. Tourmente and O. Mathieu, “MOM1 mediates DNA-methylation-independent silencing of repetitive sequences in Arabidopsis.”, EMBO Rep., vol. 7 (12) , pp. 1273–8, 2006.
  • 2005
    • O. Mathieu, A. Probst and J. Paszkowski, “Distinct regulation of histone H3 methylation at lysines 27 and 9 by CpG methylation in Arabidopsis.”, EMBO J., vol. 24 (15) , pp. 2783–91, 2005.
  • 2004
    • O. Mathieu and J. Bender, “RNA-directed DNA methylation.”, Journal of cell science, vol. 117 (Pt 21) , pp. 4881–8, 2004.
  • 2003
    • O. Mathieu, Z. Jasencakova, I. Vaillant, A. Gendrel, V. Colot, I. Schubert and S. Tourmente, “Changes in 5S rDNA chromatin organization and transcription during heterochromatin establishment in Arabidopsis.”, Plant Cell, vol. 15 (12) , pp. 2929–39, 2003.
    • O. Mathieu, Y. Yukawa, J. Prieto, I. Vaillant, M. Sugiura and S. Tourmente, “Identification and characterization of transcription factor IIIA and ribosomal protein L5 from Arabidopsis thaliana.”, Nucleic Acids Res., vol. 31 (9) , pp. 2424–33, 2003.
  • 2002
    • O. Mathieu, Y. Yukawa, M. Sugiura, G. Picard and S. Tourmente, “5S rRNA genes expression is not inhibited by DNA methylation in Arabidopsis.”, Plant J., vol. 29 (3) , pp. 313–23, 2002.
    • C. Cloix, S. Tutois, Y. Yukawa, O. Mathieu, C. Cuvillier, M. Espagnol, G. Picard and S. Tourmente, “Analysis of the 5S RNA pool in Arabidopsis thaliana: RNAs are heterogeneous and only two of the genomic 5S loci produce mature 5S RNA.”, Genome Res., vol. 12 (1) , pp. 132–44, 2002.
    • O. Mathieu, G. Picard and S. Tourmente, “Methylation of a euchromatin-heterochromatin transition region in Arabidopsis thaliana chromosome 5 left arm.”, Chromosome Res., vol. 10 (6) , pp. 455–66, 2002.
  • 2000
    • C. Cloix, S. Tutois, O. Mathieu, C. Cuvillier, M. Espagnol, G. Picard and S. Tourmente, “Analysis of 5S rDNA arrays in Arabidopsis thaliana: physical mapping and chromosome-specific polymorphisms.”, Genome Res., vol. 10 (5) , pp. 679–90, 2000.