Thematic 2: Reproduction and development in health and disease

Leaders :
Chazaud
Drevet / Saez
Guillot
Jagla
Mirouse
Sapin

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Research thematic

Cell differentiation is a leitmotiv in embryonic development and reproduction to produce various cell types such as germinal, epithelial or muscular cells. The environment, mainly neighboring cells or/and the physiological context, plays an essential role in orchestrating proper cell differentiation programs. Impairment of this program leads to developmental defects or to pathologies such as infertility, cancer or dystrophy. Four research groups of the GReD laboratory are studying cell differentiation at the levels of cell determination, maturation, diversification and morphogenesis of different cell types using genetic,  molecular and imaging tools in vertebrate and invertebrate animal models.

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