In a few words...
The GReD is a Research Center at Clermont-Ferrand, Auvergne Rhône Alpes region of France ...
Read moreResearch Thematics
News
Phd Thesis defense: Preethi POOVATHUMKADAVIL
Preethi POOVATHUMKADAVIL (Team “Diversification of muscle and heart cells in normal and pathological conditions”) will defend her Phd Thesis entitled:
"Bioinformatic and functional analyses of muscle cell diversification in Drosophila melanogaster".
Friday the 23th of April 2021 at 8:30 am- online (link avilable from Preethi)
Viva examiners : Athanasia Sotiropoulos (Cochin Inst, Paris-Reviewer); Michael V. Taylor (Cardiff University, Cardiff-Reviewer); Maria Spletter (Ludwig-Maximilians-Universität, München-Reviewer); Laurence Dubois (CBI, Toulouse -Examiner) ; Maria Eugenia Gallego (iGReD- Examiner); Krzysztof Jagla (iGReD-PhD supervisor).
Diversity matters
Blood cell progenitors play an essential role in the cellular immune response to infection but the importance of their heterogeneity remains elusive. In collaboration with the team of Pr M. Inamdar (JNCASR- Bangalore), the team “Epigenetic regulation and hematopoiesis” revealed that Drosophila larval blood cell progenitors exhibit an unforeseen degree of diversity, which underlies a proper immune response. This study has beeen published (Rodriguez et al., 2021) in elife.
This study has been higlighted on the INSB CNRS website
fixed-term contract for Research Engineer "Towards the development of better tools for the evaluation and conservation of male gametes".
Research Engineer position ( fixed-term contract 24 months) is available from june 2021 in the team "Mechanisms of mammalian post-testicular infertility"
Form more details an dapply , it's here
La vie au GReD à travers les yeux de Laura….
Du 8 au 12 février, Laura Thirouard, doctorante dans l’équipe « Environnement, Métabolisme, spermatogénèse, pathophysiologie et hérédité », sera aux manettes de la « La Bio au Labo ».
Ce media invite chaque semaine un acteur de la recherche en biologie à présenter et vulgariser ses travaux et partager son vécu.
A retrouver sur
https://labioaulabo.tumblr.com/
Twitter : @laBioauLabo https://twitter.com/laBioauLabo
Facebook : https://www.facebook.com/labioaulabo
Instagram : https://www.instagram.com/labioaulabo/?hl=fr
When LXR plays firefighters….
Chronic inflammation is a precursor mechanism supporting cancer development. Regarding the prostate, although hormone deprivation therapy significantly slows down cancer development, it triggers deep alterations in the tumor microenvironment. In its last studi, published in Genome Biology ( Bousset et al.) the NuReP team shows that the absence of nuclear receptors LXR leads to reprogramming of the tumor microenvironment, in particular the immune landscape.
Labellisation LIGUE de l’équipe MOP@ET
Félicitation à l’équipe MOP@ET qui vient d’obtenir la labélisation de La Ligue Nationale Contre le Cancer pour une période de 5 ans. Ce label prestigieux est une reconnaissance du travail mené depuis plusieurs années par cette équipe sur le cancer de la surrénale.
Ce succés mérité fait l'objet d'un article dans La Montagne
Replicate to repress
Heterochromatin, which states for highly condensed genomics regions, is mainly constituted of transcriptionally repressed repeated elements. In its last study, published in Genome Biology (Bourguet et al., 2020), the SILENT team shows that DNA polymerase epsilon, which is involved in DNA replication, plays a crucial role in maintaining both the structure and the function of heterochromatin.
Post-doc available : “Identification of natural extracts targeting LXR nuclear receptors activity involved in skin wound healing”
A 2 years post-doc position, shared between the GRed and GREENTECH company, is available in the "Nuclear receptors and prostate diseases" from august 2021
For more details and to apply, it’s here.