Emilie BRASSET
Chef d'équipe
BRASSET
Emilie
Chef d'équipe
PU
Publications
How classical genetics uncovered key determinants of TE silencing.
Published on 25 Mar 2026 in Nature Reviews Genetics
The transcription factor Traffic jam orchestrates the somatic piRNA pathway in Drosophila ovaries.
Published on 22 Apr 2025 in Cell reports , vol. 44 - pp 115453
Alizada A, Martins A , Mouniée N, Rodriguez Suarez JV, Bertin B , Gueguen N , Mirouse V , Papameletiou AM, Rivera AJ, Lau NC, Akkouche A , Maupetit-Méhouas S, Hannon GJ, Czech Nicholson B, Brasset E
Binding of heterochromatin protein Rhino to a subset of piRNA clusters depends on a combination of two histone marks.
Published on 17 Jun 2025 in Nature structural & molecular biology
Akkouche A , Kneuss E, Bornelöv S, Renaud Y , Eastwood EL, van Lopik J, Gueguen N , Jiang M, Creixell P, Maupetit Mehouas S , Sobieszek A, Gui Y, Czech Nicholson B*, Brasset E* , Hannon GJ*
Gap junctions allow transfer of metabolites between germ cells and somatic cells to promote germ cell growth in the Drosophila ovary.
Published on 18 Feb 2025 in PLoS biology , vol. 23 - pp e3003045
Vachias C , Tourlonias C , Grelée L , Gueguen N , Renaud Y , Venugopal P , Richard G , Pouchin P , Brasset E , Mirouse V
Reactivation of a somatic errantivirus and germline invasion in Drosophila ovaries.
Published on 29 Sep 2023 in Nature communications , vol. 14 - pp 6096
Yoth M , Maupetit-Méhouas S , Akkouche A , Gueguen N , Bertin B , Jensen S , Brasset E
The catalytic-dead Pcif1 regulates gene expression and fertility in Drosophila.
Published on 01 May 2023 in RNA (New York, N.Y.) , vol. 29 - pp 609-619
Franco G, Taillebourg E, Delfino E, Homolka D, Gueguen N , Brasset E , Pandey RR, Pillai RS, Fauvarque MO
The histone demethylase Kdm3 prevents auto-immune piRNAs production in Drosophila.
Published on 07 Apr 2023 in Science advances , vol. 9 - pp eade3872
Casier K, Autaa J, Gueguen N , Delmarre V, Marie PP, Ronsseray S, Carré C, Brasset E , Teysset L, Boivin A
More than just an inert dense region.
Published on 14 Oct 2022 in eLife , vol. 11
The Intricate Evolutionary Balance between Transposable Elements and Their Host: Who Will Kick at Goal and Convert the Next Try?
Published on 06 May 2022 in Biology , vol. 11
The Class I HDAC Inhibitor, MS-275, Prevents Oxaliplatin-Induced Chronic Neuropathy and Potentiates Its Antiproliferative Activity in Mice.
Published on 22 Dec 2021 in International journal of molecular sciences , vol. 23
Lamoine S, Cumenal M, Barriere DA, Pereira V, Fereyrolles M, Prival L, Barbier J, Boudieu L, Brasset E , Bertin B , Renaud Y , Miot-Noirault E, Civiale MA, Balayssac D, Aissouni Y, Eschalier A, Busserolles J
Rhino breaks the deadlock in Drosophila testis.
Published on 02 Sep 2021 in PLoS genetics , vol. 17 - pp e1009702
Molla Herman A, Brasset E
Epigenetic Requirements for Triggering Heterochromatinization and Piwi-Interacting RNA Production from Transgenes in the Drosophila Germline.
Published on 10 Apr 2020 in Cells , vol. 9
Komarov PA, Sokolova O, Akulenko N, Brasset E , Jensen S , Kalmykova A
Conserved Small Nucleotidic Elements at the Origin of Concerted piRNA Biogenesis from Genes and lncRNAs.
Published on 18 Jun 2020 in Cells , vol. 9
Jensen S , Brasset E , Parey E, Roest Crollius H, Sharakhov IV, Vaury C
flam piRNA precursors channel from the nucleus to the cytoplasm in a temporally regulated manner along Drosophila oogenesis.
Published on 06 Jul 2019 in Mobile DNA , vol. 10 - pp 28
Environmentally-induced epigenetic conversion of a piRNA cluster.
Published on 15 Mar 2019 in eLife , vol. 8
Casier K, Delmarre V, Gueguen N , Hermant C, Viodé E, Vaury C , Ronsseray S, Brasset E , Teysset L, Boivin A
sRNAPipe: a Galaxy-based pipeline for bioinformatic in-depth exploration of small RNAseq data.
Published on 01 Jan 2018 in Mobile DNA , vol. 9 - pp 25
Pogorelcnik R , Vaury C , Pouchin P , Jensen S , Brasset E
The interplay between the Argonaute proteins Piwi and Aub within Drosophila germarium is critical for oogenesis, piRNA biogenesis and TE silencing.
Published on 02 Nov 2018 in Nucleic acids research , vol. 46 - pp 10052-10065
Théron E, Maupetit-Mehouas S, Pouchin P , Baudet L , Brasset E , Vaury C
Export of piRNA precursors by EJC triggers assembly of cytoplasmic Yb-body in Drosophila.
Published on 08 Dec 2016 in Nature communications , vol. 7 - pp 13739
Increased production of piRNAs from euchromatic clusters and genes in Anopheles gambiae compared with Drosophila melanogaster.
Published on 27 Nov 2015 in Epigenetics & chromatin , vol. 8 - pp 50
George P, Jensen S , Pogorelcnik R , Lee J, Xing Y, Brasset E , Vaury C , Sharakhov IV
PIWI Slicing and RNA Elements in Precursors Instruct Directional Primary piRNA Biogenesis.
Published on 21 Jul 2015 in Cell reports , vol. 12 - pp 418-28
Homolka D, Pandey RR, Goriaux C , Brasset E , Vaury C , Sachidanandam R, Fauvarque MO, Pillai RS
History of the discovery of a master locus producing piRNAs: the flamenco/COM locus in Drosophila melanogaster.
Published on 04 Aug 2014 in Frontiers in genetics , vol. 5 - pp 257
Distinct features of the piRNA pathway in somatic and germ cells: from piRNA cluster transcription to piRNA processing and amplification.
Published on 20 Dec 2014 in Mobile DNA , vol. 5 - pp 28
Microsporidian genomes harbor a diverse array of transposable elements that demonstrate an ancestry of horizontal exchange with metazoans.
Published on 28 Aug 2014 in Genome biology and evolution , vol. 6 - pp 2289-300
Parisot N, Pelin A, Gasc C, Polonais V, Belkorchia A, Panek J, El Alaoui H, Biron DG, Brasset E , Vaury C , Peyret P, Corradi N, Peyretaillade É, Lerat E
NucBase, an easy to use read mapper for small RNAs.
Published on 01 Jan 2013 in Mobile DNA , vol. 4 - pp 1
Epigenetics and transgenerational inheritance.
Published on 24 May 2013 in Genome biology , vol. 14 - pp 306
Brasset E , Chambeyron S
Polycomb group-dependent, heterochromatin protein 1-independent, chromatin structures silence retrotransposons in somatic tissues outside ovaries.
Published on 30 Dec 2011 in DNA research : an international journal for rapid publication of reports on genes and genomes , vol. 18 - pp 451-61
The Idefix enhancer-blocking insulator also harbors barrier activity.
Published on 15 Jan 2010 in Gene , vol. 450 - pp 25-31
Genomic environment influences the dynamics of the tirant LTR retrotransposon in Drosophila.
Published on 30 May 2009 in FASEB journal : official publication of the Federation of American Societies for Experimental Biology , vol. 23 - pp 1482-9
Fablet M, Lerat E, Rebollo R, Horard B, Burlet N, Martinez S, Brasset E , Gilson E, Vaury C , Vieira C
Functional characteristics of a highly specific integrase encoded by an LTR-retrotransposon.
Published on 11 Sep 2008 in PloS one , vol. 3 - pp e3185
Faye B, Arnaud F, Peyretaillade E, Brasset E , Dastugue B, Vaury C
Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription.
Published on 20 Feb 2008 in PloS one , vol. 3 - pp e1661
Palstra RJ, Simonis M, Klous P, Brasset E , Eijkelkamp B, de Laat W
Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions.
Published on 12 Jun 2008 in Nature , vol. 453 - pp 948-51
Guelen L, Pagie L, Brasset E , Meuleman W, Faza MB, Talhout W, Eussen BH, de Klein A, Wessels L, de Laat W, van Steensel B
Idefix insulator activity can be modulated by nearby regulatory elements.
Published on 01 Jan 2007 in Nucleic acids research , vol. 35 - pp 2661-70
Brasset E , Bantignies F, Court F , Cheresiz S, Conte C, Vaury C
Viral particles of the endogenous retrovirus ZAM from Drosophila melanogaster use a pre-existing endosome/exosome pathway for transfer to the oocyte.
Published on 09 May 2006 in Retrovirology , vol. 3 - pp 25
Brasset E , Taddei AR, Arnaud F, Faye B, Fausto AM, Mazzini M, Giorgi F, Vaury C
Insulators are fundamental components of the eukaryotic genomes.
Published on 30 Jun 2005 in Heredity , vol. 94 - pp 571-6
