Franck COURT

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34 publications

Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment.

Published on 30 Jan 2024 in HGG advances , vol. 5 - pp 100271

Rengifo Rojas C , Cercy J , Perillous S , Gonthier-Guéret C, Montibus B , Maupetit-Méhouas S, Espinadel A , Dupré M , Hong CC, Hata K, Nakabayashi K, Plagge A, Bouschet T, Arnaud P , Vaillant I , Court F


L1 chimeric transcripts are expressed in healthy brain and their deregulation in glioma follows that of their host locus.

Published on 17 Aug 2022 in Human molecular genetics , vol. 31 - pp 2606-2622

Pinson ME , Court F , Masson A , Renaud Y , Fantini A , Bacoeur-Ouzillou O, Barriere M, Pereira B, Guichet PO, Chautard E, Karayan-Tapon L, Verrelle P, Arnaud P , Vaurs-Barrière C

The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation.

Published on 25 Apr 2022 in International journal of molecular sciences , vol. 23

Le Boiteux E , Guichet PO, Masliantsev K, Montibus B , Vaurs-Barriere C, Gonthier-Gueret C, Chautard E, Verrelle P, Karayan-Tapon L, Fogli A , Court F , Arnaud P


Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage.

Published on 30 Aug 2021 in Molecular oncology , vol. 15 - pp 1995-2010

Le Boiteux E , Court F , Guichet PO, Vaurs-Barrière C , Vaillant I , Chautard E, Verrelle P, Costa BM, Karayan-Tapon L, Fogli A , Arnaud P


TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment.

Published on 30 Jan 2021 in Cellular and molecular life sciences : CMLS , vol. 78 - pp 757-768

Montibus B , Cercy J , Bouschet T, Charras A, Maupetit-Méhouas S , Nury D , Gonthier-Guéret C, Chauveau S , Allegre N , Chariau C, Hong CC, Vaillant I , Marques CJ, Court F , Arnaud P


Transcriptional alterations in glioma result primarily from DNA methylation-independent mechanisms.

Published on 30 Oct 2019 in Genome research , vol. 29 - pp 1605-1621

Court F , Le Boiteux E , Fogli A , Müller-Barthélémy M, Vaurs-Barrière C , Chautard E, Pereira B, Biau J, Kemeny JL, Khalil T, Karayan-Tapon L, Verrelle P, Arnaud P


Recommendations for a nomenclature system for reporting methylation aberrations in imprinted domains.

Published on 01 Jan 2018 in Epigenetics , vol. 13 - pp 117-121

Monk D, Morales J, den Dunnen JT, Russo S, Court F , Prawitt D, Eggermann T, Beygo J, Buiting K, Tümer Z, Nomenclature group of the European Network for Human Congenital Imprinting Disorders

High-salt-recovered sequences are associated with the active chromosomal compartment and with large ribonucleoprotein complexes including nuclear bodies.

Published on 30 Nov 2018 in Genome research , vol. 28 - pp 1733-1746

Baudement MO, Cournac A, Court F , Seveno M, Parrinello H, Reynes C, Sabatier R, Bouschet T, Yi Z, Sallis S, Tancelin M, Rebouissou C, Cathala G, Lesne A, Mozziconacci J, Journot L, Forné T

CLIFinder: identification of LINE-1 chimeric transcripts in RNA-seq data.

Published on 15 Feb 2018 in Bioinformatics (Oxford, England) , vol. 34 - pp 688-690

Pinson ME , Pogorelcnik R , Court F , Arnaud P , Vaurs-Barrière C

DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34(+) CD15(-) cells in early chronic-phase chronic myeloid leukemia.

Published on 30 Jun 2018 in Molecular oncology , vol. 12 - pp 814-829

Maupetit-Mehouas S , Court F , Bourgne C, Guerci-Bresler A, Cony-Makhoul P, Johnson H, Etienne G, Rousselot P, Guyotat D, Janel A, Hermet E, Saugues S, Berger J, Arnaud P , Berger MG


Quantitative Analysis of Intra-chromosomal Contacts: The 3C-qPCR Method.

Published on 01 Jan 2017 in Methods in molecular biology (Clifton, N.J.) , vol. 1589 - pp 75-88

Ea V, Court F , Forné T

DNA methylation profiling identifies PTRF/Cavin-1 as a novel tumor suppressor in Ewing sarcoma when co-expressed with caveolin-1.

Published on 01 Feb 2017 in Cancer letters , vol. 386 - pp 196-207

Huertas-Martínez J, Court F , Rello-Varona S, Herrero-Martín D, Almacellas-Rabaiget O, Sáinz-Jaspeado M, Garcia-Monclús S, Lagares-Tena L, Buj R, Hontecillas-Prieto L, Sastre A, Azorin D, Sanjuan X, López-Alemany R, Moran S, Roma J, Gallego S, Mora J, García Del Muro X, Giangrande PH, Peinado MA, Alonso J, de Alava E, Monk D, Esteller M, Tirado OM

Maternal mutations of FOXF1 cause alveolar capillary dysplasia despite not being imprinted.

Published on 30 Jun 2017 in Human mutation , vol. 38 - pp 615-620

Alsina Casanova M, Monteagudo-Sánchez A, Rodiguez Guerineau L, Court F , Gazquez Serrano I, Martorell L, Rovira Zurriaga C, Moore GE, Ishida M, Castañon M, Moliner Calderon E, Monk D, Moreno Hernando J


Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive.

Published on 29 Jan 2016 in Nucleic acids research , vol. 44 - pp 621-35

Maupetit-Méhouas S , Montibus B , Nury D , Tayama C, Wassef M, Kota SK, Fogli A , Cerqueira Campos F , Hata K, Feil R, Margueron R, Nakabayashi K, Court F , Arnaud P

The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival.

Published on 01 Mar 2016 in Carcinogenesis , vol. 37 - pp 169-176

Fogli A , Chautard E, Vaurs-Barrière C , Pereira B, Müller-Barthélémy M, Court F , Biau J, Pinto AA, Kémény JL, Khalil T, Karayan-Tapon L, Verrelle P, Costa BM, Arnaud P

Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting.

Published on 30 Nov 2016 in PLoS genetics , vol. 12 - pp e1006427

Sanchez-Delgado M, Court F , Vidal E, Medrano J, Monteagudo-Sánchez A, Martin-Trujillo A, Tayama C, Iglesias-Platas I, Kondova I, Bontrop R, Poo-Llanillo ME, Marques-Bonet T, Nakabayashi K, Simón C, Monk D


Genome-wide parent-of-origin DNA methylation analysis reveals the intricacies of human imprinting and suggests a germline methylation-independent mechanism of establishment.

Published on 30 Apr 2014 in Genome research , vol. 24 - pp 554-69

Court F , Tayama C, Romanelli V, Martin-Trujillo A, Iglesias-Platas I, Okamura K, Sugahara N, Simón C, Moore H, Harness JV, Keirstead H, Sanchez-Mut JV, Kaneki E, Lapunzina P, Soejima H, Wake N, Esteller M, Ogata T, Hata K, Nakabayashi K, Monk D

Hypermethylation of the alternative AWT1 promoter in hematological malignancies is a highly specific marker for acute myeloid leukemias despite high expression levels.

Published on 09 Jan 2014 in Journal of hematology & oncology , vol. 7 - pp 4

Guillaumet-Adkins A, Richter J, Odero MD, Sandoval J, Agirre X, Catala A, Esteller M, Prósper F, Calasanz MJ, Buño I, Kwon M, Court F , Siebert R, Monk D

Chromatin immunoprecipitation indirect peaks highlight long-range interactions of insulator proteins and Pol II pausing.

Published on 20 Feb 2014 in Molecular cell , vol. 53 - pp 672-81

Liang J, Lacroix L, Gamot A, Cuddapah S, Queille S, Lhoumaud P, Lepetit P, Martin PG, Vogelmann J, Court F , Hennion M, Micas G, Urbach S, Bouchez O, Nöllmann M, Zhao K, Emberly E, Cuvier O

The PEG13-DMR and brain-specific enhancers dictate imprinted expression within the 8q24 intellectual disability risk locus.

Published on 25 Mar 2014 in Epigenetics & chromatin , vol. 7 - pp 5

Court F , Camprubi C, Garcia CV, Guillaumet-Adkins A, Sparago A, Seruggia D, Sandoval J, Esteller M, Martin-Trujillo A, Riccio A, Montoliu L, Monk D

Variable maternal methylation overlapping the nc886/vtRNA2-1 locus is locked between hypermethylated repeats and is frequently altered in cancer.

Published on 30 May 2014 in Epigenetics , vol. 9 - pp 783-90

Romanelli V, Nakabayashi K, Vizoso M, Moran S, Iglesias-Platas I, Sugahara N, Simón C, Hata K, Esteller M, Court F , Monk D


Chromatin loop organization of the junb locus in mouse dendritic cells.

Published on 30 Oct 2013 in Nucleic acids research , vol. 41 - pp 8908-25

Salem T, Gomard T, Court F , Moquet-Torcy G, Brockly F, Forné T, Piechaczyk M

Myod and H19-Igf2 locus interactions are required for diaphragm formation in the mouse.

Published on 30 Mar 2013 in Development (Cambridge, England) , vol. 140 - pp 1231-9

Borensztein M, Monnier P, Court F , Louault Y, Ripoche MA, Tiret L, Yao Z, Tapscott SJ, Forné T, Montarras D, Dandolo L

Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop.

Published on 01 Feb 2013 in Nucleic acids research , vol. 41 - pp 2171-9

Iglesias-Platas I, Court F , Camprubi C, Sparago A, Guillaumet-Adkins A, Martin-Trujillo A, Riccio A, Moore GE, Monk D

Genome-wide allelic methylation analysis reveals disease-specific susceptibility to multiple methylation defects in imprinting syndromes.

Published on 30 Apr 2013 in Human mutation , vol. 34 - pp 595-602

Court F , Martin-Trujillo A, Romanelli V, Garin I, Iglesias-Platas I, Salafsky I, Guitart M, Perez de Nanclares G, Lapunzina P, Monk D

Stability of genomic imprinting and gestational-age dynamic methylation in complicated pregnancies conceived following assisted reproductive technologies.

Published on 30 Sep 2013 in Biology of reproduction , vol. 89 - pp 50

Camprubí C, Iglesias-Platas I, Martin-Trujillo A, Salvador-Alarcon C, Rodriguez MA, Barredo DR, Court F , Monk D


Corneal transduction by intra-stromal injection of AAV vectors in vivo in the mouse and ex vivo in human explants.

Published on 01 Jan 2012 in PloS one , vol. 7 - pp e35318

Hippert C, Ibanes S, Serratrice N, Court F , Malecaze F, Kremer EJ, Kalatzis V

Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin.

Published on 01 Jan 2012 in PloS one , vol. 7 - pp e38907

Iglesias-Platas I, Martin-Trujillo A, Cirillo D, Court F , Guillaumet-Adkins A, Camprubi C, Bourc'his D, Hata K, Feil R, Tartaglia G, Arnaud P , Monk D

H19 antisense RNA can up-regulate Igf2 transcription by activation of a novel promoter in mouse myoblasts.

Published on 01 Jan 2012 in PloS one , vol. 7 - pp e37923

Tran VG, Court F , Duputié A, Antoine E, Aptel N, Milligan L, Carbonell F, Lelay-Taha MN, Piette J, Weber M, Montarras D, Pinset C, Dandolo L, Forné T, Cathala G

Characterization of novel paternal ncRNAs at the Plagl1 locus, including Hymai, predicted to interact with regulators of active chromatin.

Published on 19 Jun 2012 in PloS one , vol. 7 - pp e38907

Iglesias-Platas I, Martin-Trujillo A, Cirillo D, Court F , Guillaumet-Adkins A, Camprubi C, Bourc'his D, Hata K, Feil R, Tartaglia G, Arnaud P , Monk D


Modulated contact frequencies at gene-rich loci support a statistical helix model for mammalian chromatin organization.

Published on 01 Jan 2011 in Genome biology , vol. 12 - pp R42

Court F , Miro J, Braem C, Lelay-Taha MN, Brisebarre A, Atger F, Gostan T, Weber M, Cathala G, Forné T

Long-range chromatin interactions at the mouse Igf2/H19 locus reveal a novel paternally expressed long non-coding RNA.

Published on 30 Aug 2011 in Nucleic acids research , vol. 39 - pp 5893-906

Court F , Baniol M, Hagege H, Petit JS, Lelay-Taha MN, Carbonell F, Weber M, Cathala G, Forne T


Idefix insulator activity can be modulated by nearby regulatory elements.

Published on 01 Jan 2007 in Nucleic acids research , vol. 35 - pp 2661-70

Brasset E , Bantignies F, Court F , Cheresiz S, Conte C, Vaury C

Franck COURT

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