Antoine MARTINEZ
Chef d'équipe
MARTINEZ
Antoine
Chef d'équipe
DR
Publications
Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.
Publié le 21 Déc 2022 dans Nature communications , vol. 13 - pp 7858
Dufour D , Dumontet T , Sahut-Barnola I, Carusi A, Onzon M , Pussard E, Wilmouth JJ , Olabe J , Lucas C , Levasseur A , Damon-Soubeyrand C , Pointud JC , Roucher-Boulez F , Tauveron I , Bossis G, Yeh ET, Breault DT, Val P , Lefrançois-Martinez AM, Martinez A
EZH2 cooperates with E2F1 to stimulate expression of genes involved in adrenocortical carcinoma aggressiveness.
Publié le 30 Août 2019 dans British journal of cancer , vol. 121 - pp 384-394
Tabbal H , Septier A , Mathieu M , Drelon C , Rodriguez S , Djari C , Batisse-Lignier M , Tauveron I , Pointud JC , Sahut-Barnola I , Ragazzon B, Assié G, Bertherat J, Lefrançois-Martinez AM , Martinez A , Val P
Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.
Publié le 26 Déc 2018 dans Proceedings of the National Academy of Sciences of the United States of America , vol. 115 - pp E12265-E12274
Mathieu M , Drelon C , Rodriguez S , Tabbal H , Septier A , Damon-Soubeyrand C , Dumontet T , Berthon A , Sahut-Barnola I , Djari C , Batisse-Lignier M , Pointud JC , Richard D, Kerdivel G, Calméjane MA, Boeva V, Tauveron I , Lefrançois-Martinez AM , Martinez A , Val P
P53/Rb inhibition induces metastatic adrenocortical carcinomas in a preclinical transgenic model.
Publié le 30 Août 2017 dans Oncogene , vol. 36 - pp 4445-4456
Batisse-Lignier M , Sahut-Barnola I , Tissier F, Dumontet T , Mathieu M , Drelon C , Pointud JC , Damon-Soubeyrand C , Marceau G , Kemeny JL, Bertherat J, Tauveron I , Val P , Martinez A , Lefrançois-Martinez AM
Mouse Models Recapitulating Human Adrenocortical Tumors: What Is Lacking?
Publié le 15 Juil 2016 dans Frontiers in endocrinology , vol. 7 - pp 93
Leccia F , Batisse-Lignier M , Sahut-Barnola I , Val P , Lefrançois-Martinez AM , Martinez A
PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease.
Publié le 22 Sep 2016 dans JCI insight , vol. 1 - pp e87958
Bram Z, Louiset E, Ragazzon B, Renouf S, Wils J, Duparc C, Boutelet I, Rizk-Rabin M, Libé R, Young J, Carson D, Vantyghem MC, Szarek E, Martinez A , Stratakis CA, Bertherat J, Lefebvre H
Editorial: Adrenal Cortex: From Physiology to Disease.
Publié le 01 Juin 2016 dans Frontiers in endocrinology , vol. 7 - pp 51
The adrenal capsule is a signaling center controlling cell renewal and zonation through Rspo3.
Publié le 15 Juin 2016 dans Genes & development , vol. 30 - pp 1389-94
Vidal V, Sacco S, Rocha AS, da Silva F, Panzolini C, Dumontet T , Doan TM, Shan J, Rak-Raszewska A, Bird T, Vainio S, Martinez A , Schedl A
WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.
Publié le 15 Fév 2014 dans Human molecular genetics , vol. 23 - pp 889-905
Berthon A , Drelon C , Ragazzon B, Boulkroun S, Tissier F, Amar L, Samson-Couterie B, Zennaro MC, Plouin PF, Skah S, Plateroti M, Lefèbvre H, Sahut-Barnola I , Batisse-Lignier M , Assié G, Lefrançois-Martinez AM , Bertherat J, Martinez A , Val P
Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation.
Publié le 03 Sep 2013 dans Proceedings of the National Academy of Sciences of the United States of America , vol. 110 - pp 14801-6
Kanczkowski W, Alexaki VI, Tran N, Großklaus S, Zacharowski K, Martinez A , Popovics P, Block NL, Chavakis T, Schally AV, Bornstein SR
WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.
Publié le 14 Oct 2013 dans Developmental cell , vol. 27 - pp 5-18
Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I , von Gise A, Pu WT, Hohenstein P, Martinez A , Schedl A
Aldo-Keto Reductases 1B in Endocrinology and Metabolism.
Publié le 02 Août 2012 dans Frontiers in pharmacology , vol. 3 - pp 148
Pastel E , Pointud JC , Volat F, Martinez A , Lefrançois-Martinez AM
The cAMP pathway and the control of adrenocortical development and growth.
Publié le 31 Mar 2012 dans Molecular and cellular endocrinology , vol. 351 - pp 28-36
de Joussineau C , Sahut-Barnola I , Levy I, Saloustros E, Val P , Stratakis CA, Martinez A
Analysis of the role of Igf2 in adrenal tumour development in transgenic mouse models.
Publié le 28 Août 2012 dans PloS one , vol. 7 - pp e44171
Drelon C , Berthon A , Ragazzon B, Tissier F, Bandiera R, Sahut-Barnola I, de Joussineau C , Batisse-Lignier M , Lefrançois-Martinez AM, Bertherat J, Martinez A , Val P
Wnt/β-catenin signalling in adrenal physiology and tumour development.
Publié le 31 Mar 2012 dans Molecular and cellular endocrinology , vol. 351 - pp 87-95
Berthon A , Martinez A , Bertherat J, Val P
Depressed levels of prostaglandin F2α in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity.
Publié le 30 Nov 2012 dans Diabetes , vol. 61 - pp 2796-806
Volat FE, Pointud JC , Pastel E , Morio B, Sion B, Hamard G, Guichardant M, Colas R, Lefrançois-Martinez AM , Martinez A
Transcriptional control of adrenal steroidogenesis: novel connection between Janus kinase (JAK) 2 protein and protein kinase A (PKA) through stabilization of cAMP response element-binding protein (CREB) transcription factor.
Publié le 23 Sep 2011 dans The Journal of biological chemistry , vol. 286 - pp 32976-85
Lefrancois-Martinez AM , Blondet-Trichard A, Binart N, Val P , Chambon C, Sahut-Barnola I , Pointud JC , Martinez A
Identification, cloning and regulation of cDNA encoding aldo-keto reductase 1B7 in the adrenal gland of two Saharan rodents Meriones libycus (Libyan jird) and Gerbillus gerbillus (gerbil).
Publié le 01 Déc 2011 dans General and comparative endocrinology , vol. 174 - pp 292-300
Mataoui-Mazari H, Amirat Z, Khammar F, Martinez A
Cushing’s syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.
Publié le 10 Juin 2010 dans PLoS genetics , vol. 6 - pp e1000980
Sahut-Barnola I , de Joussineau C , Val P , Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC , Marceau G , Sapin V , Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A
Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.
Publié le 15 Avr 2010 dans Human molecular genetics , vol. 19 - pp 1561-76
Berthon A , Sahut-Barnola I , Lambert-Langlais S, de Joussineau C , Damon-Soubeyrand C , Louiset E, Taketo MM, Tissier F, Bertherat J, Lefrançois-Martinez AM, Martinez A , Val P
Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions.
Publié le 07 Oct 2009 dans PloS one , vol. 4 - pp e7309
Lambert-Langlais S, Pointud JC , Lefrançois-Martinez AM , Volat F, Manin M, Coudoré F, Val P , Sahut-Barnola I , Ragazzon B, Louiset E, Delarue C, Lefebvre H, Urade Y, Martinez A
A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex.
Publié le 05 Mar 2009 dans Molecular and cellular endocrinology , vol. 300 - pp 197-204
Lambert-Langlais S, Val P , Guyot S, Ragazzon B, Sahut-Barnola I , De Haze A , Lefrançois-Martinez AM , Martinez A
Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7.
Publié le 02 Mar 2009 dans Journal of biochemistry , vol. 145 - pp 161-8
Kabututu Z, Manin M, Pointud JC , Maruyama T, Nagata N, Lambert S , Lefrançois-Martinez AM, Martinez A , Urade Y
24-dehydrocholesterol reductase/seladin-1: a key protein differentially involved in adrenocorticotropin effects observed in human and rat adrenal cortex.
Publié le 30 Sep 2009 dans Endocrinology , vol. 150 - pp 4180-90
Battista MC, Roberge C, Martinez A , Gallo-Payet N
Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.
Publié le 15 Sep 2009 dans Cancer research , vol. 69 - pp 7278-84
Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H, Perlemoine K, Martinez A , Bertherat J
Mouse model for bilateral adrenal hyperplasia.
Publié le 30 Juin 2009 dans Annales d'endocrinologie , vol. 70 - pp 194
Sahut-Barnola I , De Joussineau C , Val P , Lambert-Langlais S, Lefrançois-Martinez AM , Pointud JC , Marceau G , Sapin V , Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A
