Antoine MARTINEZ

Chef d'équipe
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Publications

26 publications
2022

Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.

Published on 21 Dec 2022 in Nature communications , vol. 13 - pp 7858

Dufour D , Dumontet T , Sahut-Barnola I, Carusi A, Onzon M , Pussard E, Wilmouth JJ , Olabe J , Lucas C , Levasseur A , Damon-Soubeyrand C , Pointud JC , Roucher-Boulez F , Tauveron I , Bossis G, Yeh ET, Breault DT, Val P , Lefrançois-Martinez AM, Martinez A

AKR
cortex
stress
sumo
2018

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

Published on 26 Dec 2018 in Proceedings of the National Academy of Sciences of the United States of America , vol. 115 - pp E12265-E12274

Mathieu M , Drelon C , Rodriguez S , Tabbal H , Septier A , Damon-Soubeyrand C , Dumontet T , Berthon A , Sahut-Barnola I , Djari C , Batisse-Lignier M , Pointud JC , Richard D, Kerdivel G, Calméjane MA, Boeva V, Tauveron I , Lefrançois-Martinez AM , Martinez A , Val P

AKR
2016

PKA regulatory subunit 1A inactivating mutation induces serotonin signaling in primary pigmented nodular adrenal disease.

Published on 22 Sep 2016 in JCI insight , vol. 1 - pp e87958

Bram Z, Louiset E, Ragazzon B, Renouf S, Wils J, Duparc C, Boutelet I, Rizk-Rabin M, Libé R, Young J, Carson D, Vantyghem MC, Szarek E, Martinez A , Stratakis CA, Bertherat J, Lefebvre H

AKR

Editorial: Adrenal Cortex: From Physiology to Disease.

Published on 01 Jun 2016 in Frontiers in endocrinology , vol. 7 - pp 51

Val P , Martinez A

AKR

The adrenal capsule is a signaling center controlling cell renewal and zonation through Rspo3.

Published on 15 Jun 2016 in Genes & development , vol. 30 - pp 1389-94

Vidal V, Sacco S, Rocha AS, da Silva F, Panzolini C, Dumontet T , Doan TM, Shan J, Rak-Raszewska A, Bird T, Vainio S, Martinez A , Schedl A

AKR
2014

WNT/β-catenin signalling is activated in aldosterone-producing adenomas and controls aldosterone production.

Published on 15 Feb 2014 in Human molecular genetics , vol. 23 - pp 889-905

Berthon A , Drelon C , Ragazzon B, Boulkroun S, Tissier F, Amar L, Samson-Couterie B, Zennaro MC, Plouin PF, Skah S, Plateroti M, Lefèbvre H, Sahut-Barnola I , Batisse-Lignier M , Assié G, Lefrançois-Martinez AM , Bertherat J, Martinez A , Val P

AKR
2013

Hypothalamo-pituitary and immune-dependent adrenal regulation during systemic inflammation.

Published on 03 Sep 2013 in Proceedings of the National Academy of Sciences of the United States of America , vol. 110 - pp 14801-6

Kanczkowski W, Alexaki VI, Tran N, Großklaus S, Zacharowski K, Martinez A , Popovics P, Block NL, Chavakis T, Schally AV, Bornstein SR

AKR

WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland.

Published on 14 Oct 2013 in Developmental cell , vol. 27 - pp 5-18

Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I , von Gise A, Pu WT, Hohenstein P, Martinez A , Schedl A

AKR
2012

Aldo-Keto Reductases 1B in Endocrinology and Metabolism.

Published on 02 Aug 2012 in Frontiers in pharmacology , vol. 3 - pp 148

Pastel E , Pointud JC , Volat F, Martinez A , Lefrançois-Martinez AM

The cAMP pathway and the control of adrenocortical development and growth.

Published on 31 Mar 2012 in Molecular and cellular endocrinology , vol. 351 - pp 28-36

de Joussineau C , Sahut-Barnola I , Levy I, Saloustros E, Val P , Stratakis CA, Martinez A

AKR

Analysis of the role of Igf2 in adrenal tumour development in transgenic mouse models.

Published on 28 Aug 2012 in PloS one , vol. 7 - pp e44171

Drelon C , Berthon A , Ragazzon B, Tissier F, Bandiera R, Sahut-Barnola I, de Joussineau C , Batisse-Lignier M , Lefrançois-Martinez AM, Bertherat J, Martinez A , Val P

AKR

Wnt/β-catenin signalling in adrenal physiology and tumour development.

Published on 31 Mar 2012 in Molecular and cellular endocrinology , vol. 351 - pp 87-95

Berthon A , Martinez A , Bertherat J, Val P

AKR

Depressed levels of prostaglandin F2α in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity.

Published on 30 Nov 2012 in Diabetes , vol. 61 - pp 2796-806

Volat FE, Pointud JC , Pastel E , Morio B, Sion B, Hamard G, Guichardant M, Colas R, Lefrançois-Martinez AM , Martinez A

2010

Cushing’s syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.

Published on 10 Jun 2010 in PLoS genetics , vol. 6 - pp e1000980

Sahut-Barnola I , de Joussineau C , Val P , Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC , Marceau G , Sapin V , Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A

AKR

Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development.

Published on 15 Apr 2010 in Human molecular genetics , vol. 19 - pp 1561-76

Berthon A , Sahut-Barnola I , Lambert-Langlais S, de Joussineau C , Damon-Soubeyrand C , Louiset E, Taketo MM, Tissier F, Bertherat J, Lefrançois-Martinez AM, Martinez A , Val P

AKR
2009

Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions.

Published on 07 Oct 2009 in PloS one , vol. 4 - pp e7309

Lambert-Langlais S, Pointud JC , Lefrançois-Martinez AM , Volat F, Manin M, Coudoré F, Val P , Sahut-Barnola I , Ragazzon B, Louiset E, Delarue C, Lefebvre H, Urade Y, Martinez A

AKR

A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex.

Published on 05 Mar 2009 in Molecular and cellular endocrinology , vol. 300 - pp 197-204

Lambert-Langlais S, Val P , Guyot S, Ragazzon B, Sahut-Barnola I , De Haze A , Lefrançois-Martinez AM , Martinez A

AKR

Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7.

Published on 02 Mar 2009 in Journal of biochemistry , vol. 145 - pp 161-8

Kabututu Z, Manin M, Pointud JC , Maruyama T, Nagata N, Lambert S , Lefrançois-Martinez AM, Martinez A , Urade Y

Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells.

Published on 15 Sep 2009 in Cancer research , vol. 69 - pp 7278-84

Ragazzon B, Cazabat L, Rizk-Rabin M, Assie G, Groussin L, Fierrard H, Perlemoine K, Martinez A , Bertherat J

Mouse model for bilateral adrenal hyperplasia.

Published on 30 Jun 2009 in Annales d'endocrinologie , vol. 70 - pp 194

Sahut-Barnola I , De Joussineau C , Val P , Lambert-Langlais S, Lefrançois-Martinez AM , Pointud JC , Marceau G , Sapin V , Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A

AKR

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Antoine MARTINEZ

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