Jean-Christophe POINTUD

Maitre de Conférences
institute
HomeJean-Christophe POINTUD

POINTUD
Jean-Christophe
Maitre de Conférences
MCF

Publications

13 publications
2022

Loss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.

Published on 21 Dec 2022 in Nature communications , vol. 13 - pp 7858

Dufour D , Dumontet T , Sahut-Barnola I, Carusi A, Onzon M , Pussard E, Wilmouth JJ , Olabe J , Lucas C , Levasseur A , Damon-Soubeyrand C , Pointud JC , Roucher-Boulez F , Tauveron I , Bossis G, Yeh ET, Breault DT, Val P , Lefrançois-Martinez AM, Martinez A

AKR
cortex
stress
sumo
2018

Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex.

Published on 26 Dec 2018 in Proceedings of the National Academy of Sciences of the United States of America , vol. 115 - pp E12265-E12274

Mathieu M , Drelon C , Rodriguez S , Tabbal H , Septier A , Damon-Soubeyrand C , Dumontet T , Berthon A , Sahut-Barnola I , Djari C , Batisse-Lignier M , Pointud JC , Richard D, Kerdivel G, Calméjane MA, Boeva V, Tauveron I , Lefrançois-Martinez AM , Martinez A , Val P

AKR
2014

‘Auto-click’ functionalization for diversified copper(I) and gold(I) NHCs.

Published on 21 May 2014 in Dalton transactions (Cambridge, England : 2003) , vol. 43 - pp 6981-9

Ibrahim H, Gibard C, Hesling C , Guillot R, Morel L , Gautier A, Cisnetti F

2012

Aldo-Keto Reductases 1B in Endocrinology and Metabolism.

Published on 02 Aug 2012 in Frontiers in pharmacology , vol. 3 - pp 148

Pastel E , Pointud JC , Volat F, Martinez A , Lefrançois-Martinez AM

Depressed levels of prostaglandin F2α in mice lacking Akr1b7 increase basal adiposity and predispose to diet-induced obesity.

Published on 30 Nov 2012 in Diabetes , vol. 61 - pp 2796-806

Volat FE, Pointud JC , Pastel E , Morio B, Sion B, Hamard G, Guichardant M, Colas R, Lefrançois-Martinez AM , Martinez A

2010

Cushing’s syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice.

Published on 10 Jun 2010 in PLoS genetics , vol. 6 - pp e1000980

Sahut-Barnola I , de Joussineau C , Val P , Lambert-Langlais S, Damon C, Lefrançois-Martinez AM, Pointud JC , Marceau G , Sapin V , Tissier F, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A

AKR
2009

Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions.

Published on 07 Oct 2009 in PloS one , vol. 4 - pp e7309

Lambert-Langlais S, Pointud JC , Lefrançois-Martinez AM , Volat F, Manin M, Coudoré F, Val P , Sahut-Barnola I , Ragazzon B, Louiset E, Delarue C, Lefebvre H, Urade Y, Martinez A

AKR

Prostaglandin F2alpha synthase activities of aldo-keto reductase 1B1, 1B3 and 1B7.

Published on 02 Mar 2009 in Journal of biochemistry , vol. 145 - pp 161-8

Kabututu Z, Manin M, Pointud JC , Maruyama T, Nagata N, Lambert S , Lefrançois-Martinez AM, Martinez A , Urade Y

Mouse model for bilateral adrenal hyperplasia.

Published on 30 Jun 2009 in Annales d'endocrinologie , vol. 70 - pp 194

Sahut-Barnola I , De Joussineau C , Val P , Lambert-Langlais S, Lefrançois-Martinez AM , Pointud JC , Marceau G , Sapin V , Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A

AKR

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Jean-Christophe POINTUD

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