Olivier BARDOT

Maitre de Conférences
HomeOlivier BARDOT

Maitre de Conférences


I am Associate Professor in the Biology Department of the University Institute of Technology (Auvergne) since 1995 on the Campus Cezeaux, Aubiere. I am teaching biochemistry.
I mainly studied morphogenesis during development in the Drosophila melanogaster model organism. I have developed for this work, approaches based on genetics, molecular biology and microscopy.

I am currently working on mechanisms that control the size and shape of the cells during development.


I am currently working on mechanisms that control cells size and shape during development. These two parameters must be coordinated during growth and epithelial differentiation. Deregulation of coordination often leads to the formation of tumors, most cancer tumors having an epithelial origin. As model, we use ovarian follicular cells of Drosophila melanogaster. This somatic cell monolayer surrounds the germ cells that will grow up to give a fertilized egg by increasing size during its development. Follicular cells must follow the growth of underneath tissue without loosing their properties. For this work, the approaches used are primarily
genetic and confocal microscopy imaging.

A good analogy: When we are getting fat, how the skin “follows” the deformation without leaving holes and without leaving folds when we get slim.


17 publications

Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine.

Published on 13 Aug 2014 in BMC genomics , vol. 15 - pp 679

Borrel G, Parisot N, Harris HM, Peyretaillade E, Gaci N, Tottey W, Bardot O , Raymann K, Gribaldo S, Peyret P, O'Toole PW, Brugère JF


Genome Sequence of “Candidatus Methanomassiliicoccus intestinalis” Issoire-Mx1, a Third Thermoplasmatales-Related Methanogenic Archaeon from Human Feces.

Published on 11 Jul 2013 in Genome announcements , vol. 1

Borrel G, Harris HM, Parisot N, Gaci N, Tottey W, Mihajlovski A, Deane J, Gribaldo S, Bardot O , Peyretaillade E, Peyret P, O'Toole PW, Brugère JF


Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling.

Published on 13 Dec 2011 in Developmental cell , vol. 21 - pp 1005-13

Frankenberg S, Gerbe F, Bessonnard S , Belville C , Pouchin P , Bardot O , Chazaud C


HtrA stress protein is involved in intramacrophagic replication of adherent and invasive Escherichia coli strain LF82 isolated from a patient with Crohn’s disease.

Published on 02 Mar 2005 in Infection and immunity , vol. 73 - pp 712-21

Bringer MA, Barnich N, Glasser AL, Bardot O , Darfeuille-Michaud A


Toxicological evaluation of peroxisome proliferators. Further cellular and molecular aspects.

Published on 27 Dec 1996 in Annals of the New York Academy of Sciences , vol. 804 - pp 716-8

Passilly P, Pacot C, Jannin B, Cherkaoui Malki M, Bardot O , Caira F , Clemencet MC, Latruffe N


Delayed effects of ciprofibrate on rat liver peroxisomal properties and proto-oncogene expression.

Published on 28 Sep 1995 in Biochemical pharmacology , vol. 50 - pp 1001-6

Bardot O , Clemencet MC, Cherkaoui Malki M, Latruffe N


PPAR-RXR heterodimer activates a peroxisome proliferator response element upstream of the bifunctional enzyme gene.

Published on 15 Apr 1993 in Biochemical and biophysical research communications , vol. 192 - pp 37-45

Bardot O , Aldridge TC, Latruffe N, Green S


Effect of different hypolipemic agents on rat liver peroxisomal and mitochondrial functions and biogenesis.

Published on 01 Jan 1991 in Cellular and molecular biology , vol. 37 - pp 723-33

Cherkaoui Malki M, Assaka L, Pacot C, Bardot O , Latruffe N

Molecular analysis of a human liver mitochondrial ornithine transcarbamylase deficiency.

Published on 01 Jan 1991 in Journal of inherited metabolic disease , vol. 14 - pp 29-36

Berrez JM, Bardot O , Thiard MC, Alvarez F, Latruffe N


Expression of liver peroxisomal proteins as compared to other organelle marker enzymes in rats treated with hypolipidemic agents.

Published on 01 Jan 1990 in Biology of the cell , vol. 69 - pp 83-92

Cherkaoui Malki M, Bardot O , Lhuguenot JC, Latruffe N

Olivier BARDOT

    Votre navigateur est obsolète

    Pour profiter du site,
    merci de mettre à jour votre navigateur