Francoise CAIRAMaitre de Conférences
After having worked as a teacher and then lived in Israel in the 1980s, I joined the University of Burgundy in 1987 where I defended a doctorate in Animal Physiology in 1996. I then obtained a research position at the Karolinska Institute in Stockholm before joining Blaise Pascal University in 1999 as a lecturer in the laboratory (now) GReD.
I successively held positions on collective missions as President of the Department of Biology for one term (2011-13), Director of Studies for the First Years (DEPA) in the Pedagogical Service of the Scientific License (SPLS, 2010- 16), Project Manager "Assistance for Student Success" at Blaise Pascal University (2012-2016), Vice-President in charge of Pedagogical Transformation, Digital Pedagogy and Documentary Policy (2017-21) and Director of the Pedagogical Engineering & Audiovisual Production (IPPA) Pole since 2017. In January 2021, the presidency of the EPE-UCA appointed me Strategic Director of the IPPA Pole. This function involves defining a Pedagogical Transformation strategy at UCA and deploying this policy across the establishment by leading the team of pedagogical engineers and audiovisual engineers from the service dedicated to this mission.
Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system.
Published on 30 Dec 2019 in Cellular and molecular life sciences : CMLS , vol. 76 - pp 4849-4859
Published on 30 Nov 2019 in The Journal of steroid biochemistry and molecular biology , vol. 194 - pp 105460
Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders.
Published on 09 Oct 2018 in Stem cell reports , vol. 11 - pp 944-958
Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases.
Published on 17 Nov 2018 in International journal of molecular sciences , vol. 19
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C, De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
Identification of the link between the hypothalamo-pituitary axis and the testicular orphan nuclear receptor NR0B2 in adult male mice.
Published on 02 Mar 2015 in Endocrinology , vol. 156 - pp 660-9
Liver X receptors interfere with the deleterious effect of diethylstilbestrol on testicular physiology.
Published on 11 Apr 2014 in Biochemical and biophysical research communications , vol. 446 - pp 656-62
Liver X Receptor activation downregulates AKT survival signaling in lipid rafts and induces apoptosis of prostate cancer cells.
Published on 06 May 2010 in Oncogene , vol. 29 - pp 2712-23
Absence of nuclear receptors for oxysterols liver X receptor induces ovarian hyperstimulation syndrome in mice.
Published on 30 Jul 2009 in Endocrinology , vol. 150 - pp 3369-75
Published on 02 Mar 2009 in Medecine sciences : M/S , vol. 25 - pp 141-4
Published on 30 Jul 2006 in The Journal of clinical investigation , vol. 116 - pp 1902-12
Regulation of the aldo-keto reductase gene akr1b7 by the nuclear oxysterol receptor LXRalpha (liver X receptor-alpha) in the mouse intestine: putative role of LXRs in lipid detoxification processes.
Published on 30 Apr 2004 in Molecular endocrinology (Baltimore, Md.) , vol. 18 - pp 888-98
Published on 30 Jun 2001 in Annales d'endocrinologie , vol. 62 - pp 239-47
Published on 27 Dec 1996 in Annals of the New York Academy of Sciences , vol. 804 - pp 716-8
Transcriptional and post-transcriptional analysis of peroxisomal protein encoding genes from rat treated with an hypolipemic agent, ciprofibrate. Effect of an intermittent treatment and influence of obesity.
Published on 01 Mar 1995 in Biochemical pharmacology , vol. 49 - pp 611-9