Claude BEAUDOIN
Professeur des Universités
BEAUDOIN
Claude
Professeur des Universités
PhD HDR
Publications
Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells.
Published on 26 Nov 2024 in The Journal of biological chemistry - pp 108022
Garcia M , Holota H , De Haze A , Saru JP , Sanchez P , Battistelli E , Thirouard L , Monrose M , Benoit G, Volle DH, Beaudoin C
Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt-Foxo1 Pathway.
Published on 24 Sep 2024 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) - pp e2402082
Monrose M , Holota H , Martinez G, Damon-Soubeyrand C , Thirouard L , Martinot E , Battistelli E , de Haze A , Bravard S , Tamisier C , Caira F , Coutton C, Barbotin AL, Boursier A, Lakhal L, Beaudoin C , Volle DH
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms.
Published on 29 Aug 2024 in Molecular aspects of medicine , vol. 99 - pp 101307
Pang WK , Kuznetsova E , Holota H , De Haze A , Beaudoin C , Volle DH
Metallome deregulation and health-related impacts due to long-term exposure to recent volcanic ash deposits: New chemical and isotopic insights.
Published on 10 Jul 2022 in The Science of the total environment , vol. 829 - pp 154383
Sauzéat L , Eychenne J , Gurioli L, Boyet M, Jessop DE, Moretti R, Monrose M , Holota H , Beaudoin C , Volle DH
Intestinal microbiota defines the GUT-TESTIS axis.
Published on 30 Apr 2022 in Gut , vol. 71 - pp 844-845
Martinot E , Thirouard L , Holota H , Monrose M , Garcia M , Beaudoin C , Volle DH
Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance.
Published on 30 Jun 2022 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) , vol. 9 - pp e2200626
Thirouard L , Holota H , Monrose M , Garcia M , de Haze A , Damon-Soubeyrand C, Renaud Y , Saru JP , Perino A, Schoonjans K, Beaudoin C , Volle DH
Identification of the Role of TGR5 in the Regulation of Leydig Cell Homeostasis.
Published on 06 Dec 2022 in International journal of molecular sciences , vol. 23
Holota H , De Haze A , Martinot E , Monrose M , Saru JP , Caira F , Beaudoin C , Volle DH
Metallome deregulation and health-related impacts due to long-term exposure to recent volcanic ash deposits: New chemical and isotopic insights.
Published on 10 Jul 2022 in The Science of the total environment , vol. 829 - pp 154383
Sauzéat L , Eychenne J , Gurioli L, Boyet M, Jessop DE, Moretti R, Monrose M , Holota H , Beaudoin C , Volle DH
MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin.
Published on 26 Aug 2021 in Journal of experimental & clinical cancer research : CR , vol. 40 - pp 270
Luo Y, Vlaeminck-Guillem V, Baron S , Dallel S , Zhang CX, Le Romancer M
Drosophila Accessory Gland: A Complementary In Vivo Model to Bring New Insight to Prostate Cancer.
Published on 10 Sep 2021 in Cells , vol. 10
Rambur A , Vialat M , Beaudoin C , Lours-Calet C, Lobaccaro JM , Baron S , Morel L , de Joussineau C
Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse Testes.
Published on 13 Sep 2021 in Cells , vol. 10
Thirouard L , Holota H , Monrose M , Garcia M , De Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100886
Monrose M , Thirouard L , Garcia M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Nuclear receptors in physiology and pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100956
Multiple functions of the scaffold protein Discs large 5 in the control of growth, cell polarity and cell adhesion in Drosophila melanogaster.
Published on 18 Jun 2020 in BMC developmental biology , vol. 20 - pp 10
Venugopal P , Veyssière H , Couderc JL , Richard G , Vachias C , Mirouse V
Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation.
Published on 08 Apr 2020 in Development (Cambridge, England) , vol. 147
Cerqueira Campos F , Dennis C , Alégot H , Fritsch C , Isabella A, Pouchin P , Bardot O , Horne-Badovinac S, Mirouse V
Sequential Ras/MAPK and PI3K/AKT/mTOR pathways recruitment drives basal extrusion in the prostate-like gland of Drosophila.
Published on 08 May 2020 in Nature communications , vol. 11 - pp 2300
Rambur A , Lours-Calet C, Beaudoin C , Buñay J, Vialat M , Mirouse V , Trousson A , Renaud Y , Lobaccaro JA, Baron S , Morel L , de Joussineau C
Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system.
Published on 30 Dec 2019 in Cellular and molecular life sciences : CMLS , vol. 76 - pp 4849-4859
Garcia M , Thirouard L , Monrose M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis.
Published on 30 Nov 2019 in The Journal of steroid biochemistry and molecular biology , vol. 194 - pp 105460
Holota H , Thirouard L , Garcia M , Monrose M , de Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
Cholesterol: A Gatekeeper of Male Fertility?
Published on 01 Jul 2018 in Frontiers in endocrinology , vol. 9 - pp 369
Sèdes L , Thirouard L , Maqdasy S , Garcia M , Caira F , Lobaccaro JA, Beaudoin C , Volle DH
Crosstalk between BPA and FXRα Signaling Pathways Lead to Alterations of Undifferentiated Germ Cell Homeostasis and Male Fertility Disorders.
Published on 09 Oct 2018 in Stem cell reports , vol. 11 - pp 944-958
Sèdes L , Desdoits-Lethimonier C, Rouaisnel B , Holota H , Thirouard L , Lesne L, Damon-Soubeyrand C, Martinot E , Saru JP , Mazaud-Guittot S, Caira F , Beaudoin C , Jégou B, Volle DH
Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways.
Published on 15 Nov 2018 in Scientific reports , vol. 8 - pp 16875
Baptissart M , Sèdes L , Holota H , Thirouard L , Martinot E , de Haze A , Rouaisnel B , Caira F , Beaudoin C , Volle DH
Nuclear Receptor Metabolism of Bile Acids and Xenobiotics: A Coordinated Detoxification System with Impact on Health and Diseases.
Published on 17 Nov 2018 in International journal of molecular sciences , vol. 19
Garcia M , Thirouard L , Sedès L , Monrose M , Holota H , Caira F , Volle DH , Beaudoin C
Bile acids and male fertility: From mouse to human?
Published on 01 Aug 2017 in Molecular aspects of medicine , vol. 56 - pp 101-109
Sèdes L , Martinot E , Baptissart M , Baron S , Caira F , Beaudoin C , Volle DH
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C , De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
Bile acids and their receptors.
Published on 30 Aug 2017 in Molecular aspects of medicine , vol. 56 - pp 2-9
Martinot E , Sèdes L , Baptissart M , Lobaccaro JM , Caira F , Beaudoin C , Volle DH
Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
Published on 09 Feb 2017 in Scientific reports , vol. 7 - pp 42182
Martinot E , Baptissart M , Véga A , Sèdes L , Rouaisnel B , Vaz F, Saru JP , de Haze A , Baron S , Caira F , Beaudoin C , Volle DH
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C, De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
Bile acids and male fertility: From mouse to human?
Published on 30 Aug 2017 in Molecular aspects of medicine , vol. 56 - pp 101-109
Sèdes L , Martinot E , Baptissart M , Baron S , Caira F , Beaudoin C , Volle DH
ERRα induces H3K9 demethylation by LSD1 to promote cell invasion.
Published on 11 Apr 2017 in Proceedings of the National Academy of Sciences of the United States of America , vol. 114 - pp 3909-3914
Carnesecchi J, Forcet C, Zhang L, Tribollet V, Barenton B, Boudra R , Cerutti C, Billas IM, Sérandour AA, Carroll JS, Beaudoin C , Vanacker JM
Lipid Homeostasis and Ligands for Liver X Receptors: Identification and Characterization.
Published on 01 Jan 2016 in Methods in molecular biology (Clifton, N.J.) , vol. 1443 - pp 13-9
Lobaccaro JM , Beaudoin C , Bayala B , Baron S , Trousson A
STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma.
Published on 30 Jan 2016 in Brain pathology (Zurich, Switzerland) , vol. 26 - pp 18-30
Ouédraogo ZG, Müller-Barthélémy M, Kemeny JL, Dedieu V, Biau J, Khalil T, Raoelfils LI, Granzotto A, Pereira B, Beaudoin C , Guissou IP, Berger M, Morel L , Chautard E, Verrelle P
mTOR transcriptionally and post-transcriptionally regulates Npm1 gene expression to contribute to enhanced proliferation in cells with Pten inactivation.
Published on 18 May 2016 in Cell cycle (Georgetown, Tex.) , vol. 15 - pp 1352-62
Boudra R , Lagrafeuille R, Lours-Calet C, de Joussineau C , Loubeau-Legros G, Chaveroux C, Saru JP , Baron S , Morel L , Beaudoin C
NPM1 silencing reduces tumour growth and MAPK signalling in prostate cancer cells.
Published on 05 May 2014 in PloS one , vol. 9 - pp e96293
Loubeau G, Boudra R , Maquaire S, Lours-Calet C, Beaudoin C , Verrelle P, Morel L
Toxicity of copper(I)-NHC complexes against human tumor cells: induction of cell cycle arrest, apoptosis, and DNA cleavage.
Published on 01 Jan 2009 in Chemistry (Weinheim an der Bergstrasse, Germany) , vol. 15 - pp 314-8
Teyssot ML, Jarrousse AS, Chevry A, De Haze A , Beaudoin C , Manin M, Nolan SP, Díez-González S, Morel L , Gautier A
[NPM: a new player in prostate cancer?].
Published on 30 Jan 2009 in Medecine sciences : M/S , vol. 25 - pp 19-21
Beaudoin C , Maquaire S, Léotoing L, Allemand J, Lours-Calet C, Veyssière G, Manin M, Morel L
Metal-NHC complexes: a survey of anti-cancer properties.
Published on 21 Sep 2009 in Dalton transactions (Cambridge, England : 2003) - pp 6894-902
Teyssot ML, Jarrousse AS, Manin M, Chevry A, Roche S, Norre F, Beaudoin C , Morel L , Boyer D, Mahiou R, Gautier A
Influence of nucleophosmin/B23 on DNA binding and transcriptional activity of the androgen receptor in prostate cancer cell.
Published on 01 May 2008 in Oncogene , vol. 27 - pp 2858-67
Léotoing L, Meunier L, Manin M, Mauduit C, Decaussin M, Verrijdt G, Claessens F, Benahmed M, Veyssière G, Morel L , Beaudoin C
