Fabrice SAEZ
Maitre de Conférences
SAEZ
Fabrice
Maitre de Conférences
MCF
Platforms
Publications
Loss of Nuclear/DNA Integrity in Mouse Epididymal Spermatozoa after Short-Term Exposure to Low Doses of Dibutyl Phthalate or Bisphenol AF and Its Mitigation by Oral Antioxidant Supplementation.
Published on 05 May 2023 in Antioxidants (Basel, Switzerland) , vol. 12
Hug E , Villeneuve P , Bravard S , Chorfa A , Damon-Soubeyrand C , Somkuti SG, Moazamian A , Aitken RJ, Gharagozloo P, Drevet JR , Saez F
Spermatozoa isolation with Felix™ outperforms conventional density gradient centrifugation preparation in selecting cells with low DNA damage.
Published on 11 Jan 2023 in Andrology
Villeneuve P , Saez F , Hug E , Chorfa A , Guiton R , Schubert B, Force A, Drevet JR
Three-dimensional imaging of vascular development in the mouse epididymis.
Published on 13 Jun 2023 in eLife , vol. 12
Damon-Soubeyrand C , Bongiovanni A, Chorfa A , Goubely C , Pirot N, Pardanaud L, Piboin-Fragner L, Vachias C , Bravard S , Guiton R , Thomas JL, Saez F , Kocer A , Tardivel M, Drevet JR , Henry-Berger J
Sexual discrimination and attraction through scents in the water vole, Arvicola terrestris.
Published on 10 Sep 2023 in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
Poissenot K, Trouillet AC, Trives E, Moussu C, Chesneau D, Meunier M, Lattard V, Chorfa A , Saez F , Drevet J , Le Danvic C, Nagnan-Le Meillour P, Chamero P, Keller M
When idiopathic male infertility is rooted in maternal malnutrition during the perinatal period in mice†.
Published on 19 Mar 2022 in Biology of reproduction , vol. 106 - pp 463-476
Muranishi Y, Parry L, Vachette-Dit-Martin M, Saez F , Coudy-Gandilhon C, Sauvanet P, Volle DH , Tournayre J, Bottari S, Carpentiero F, Martinez G, Muroňová J, Escoffier J, Bruhat A, Maurin AC, Averous J, Arnoult C, Fafournoux P, Jousse C
Field study reveals morphological and neuroendocrine correlates of seasonal breeding in female water voles, Arvicola terrestris.
Published on 15 Sep 2021 in General and comparative endocrinology , vol. 311 - pp 113853
Poissenot K , Moussu C, Chesneau D, Ramadier E, Abi Khalil R, Chorfa A , Chemineau P, Michelin Y, Saez F , Drevet J , Benoit E, Lattard V, Pinot A, Dardente H, Keller M
Identification of Arvicola terrestris scherman Sperm Antigens for Immune Contraceptive Purposes.
Published on 15 Sep 2021 in International journal of molecular sciences , vol. 22
Chorfa A , Goubely C , Henry-Berger J , Guiton R , Drevet JR , Saez F
Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis.
Published on 22 Jan 2020 in Scientific reports , vol. 10 - pp 995
Voisin A , Damon-Soubeyrand C , Bravard S , Saez F , Drevet JR , Guiton R
Of vessels and cells: the spatial organization of the epididymal immune system.
Published on 01 Sep 2019 in Andrology , vol. 7 - pp 712-718
Guiton R , Voisin A , Henry-Berger J , Saez F , Drevet JR
Impairment of sperm maturation and capacitation due to diet-dependent cholesterol overload.
Published on 01 Sep 2019 in Andrology , vol. 7 - pp 654-661
Dietary Cholesterol and Lipid Overload: Impact on Male Fertility.
Published on 06 Dec 2019 in Oxidative medicine and cellular longevity , vol. 2019 - pp 4521786
The epididymal immune balance: a key to preserving male fertility.
Published on 01 Nov 2019 in Asian journal of andrology , vol. 21 - pp 531-539
Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
Published on 01 Aug 2018 in Molecular reproduction and development , vol. 85 - pp 682-695
El Khouri E, Whitfield M , Stouvenel L, Kini A, Riederer B, Lores P, Roemermann D, di Stefano G, Drevet JR , Saez F , Seidler U, Touré A
Comprehensive overview of murine epididymal mononuclear phagocytes and lymphocytes: Unexpected populations arise.
Published on 01 Apr 2018 in Journal of reproductive immunology , vol. 126 - pp 11-17
Voisin A , Whitfield M , Damon-Soubeyrand C , Goubely C , Henry-Berger J , Saez F , Kocer A , Drevet JR , Guiton R
Dual extraction of mRNA and lipids from a single biological sample.
Published on 04 May 2018 in Scientific reports , vol. 8 - pp 7019
Podechard N, Ducheix S, Polizzi A, Lasserre F, Montagner A, Legagneux V, Fouché E, Saez F , Lobaccaro JM , Lakhal L, Ellero-Simatos S, Martin PG, Loiseau N, Bertrand-Michel J, Guillou H
Nuclear Integrity but Not Topology of Mouse Sperm Chromosome is Affected by Oxidative DNA Damage.
Published on 17 Oct 2018 in Genes , vol. 9
Champroux A , Damon-Soubeyrand C , Goubely C , Bravard S , Henry-Berger J , Guiton R , Saez F , Drevet J , Kocer A
Dyslipidemia alters sperm maturation and capacitation in LXR-null mice.
Published on 01 Dec 2017 in Reproduction (Cambridge, England) , vol. 154 - pp 827-842
Whitfield M , Guiton R , Rispal J , Acar N, Kocer A , Drevet JR , Saez F
Liver X Receptors (LXRs) Alpha and Beta Play Distinct Roles in the Mouse Epididymis.
Published on 01 Mar 2016 in Biology of reproduction , vol. 94 - pp 55
Whitfield M , Ouvrier A, Cadet R , Damon-Soubeyrand C , Guiton R , Janny L , Kocer A , Marceau G , Pons-Rejraji H , Trousson A , Drevet JR , Saez F
Posttesticular sperm maturation, infertility, and hypercholesterolemia.
Published on 01 Sep 2015 in Asian journal of andrology , vol. 17 - pp 742-8
Whitfield M , Pollet-Villard X, Levy R, Drevet JR , Saez F
Oxidative DNA damage in mouse sperm chromosomes: Size matters.
Published on 01 Dec 2015 in Free radical biology & medicine , vol. 89 - pp 993-1002
Kocer A , Henry-Berger J , Noblanc A , Champroux A , Pogorelcnik R , Guiton R , Janny L , Pons-Rejraji H , Saez F , Johnson GD, Krawetz SA, Alvarez JG, Aitken RJ, Drevet JR
Indoleamine 2,3-dioxygenase 1 (ido1) is involved in the control of mouse caput epididymis immune environment.
Published on 20 Jun 2013 in PloS one , vol. 8 - pp e66494
Jrad-Lamine A , Henry-Berger J , Damon-Soubeyrand C , Saez F , Kocer A , Janny L , Pons-Rejraji H , Munn DH, Mellor AL, Gharbi N, Cadet R , Guiton R , Aitken RJ, Drevet JR
DNA oxidative damage in mammalian spermatozoa: where and why is the male nucleus affected?
Published on 01 Dec 2013 in Free radical biology & medicine , vol. 65 - pp 719-723
Noblanc A , Damon-Soubeyrand C , Karrich B, Henry-Berger J , Cadet R , Saez F , Guiton R , Janny L , Pons-Rejraji H , Alvarez JG, Drevet JR , Kocer A
Epididymis response partly compensates for spermatozoa oxidative defects in snGPx4 and GPx5 double mutant mice.
Published on 01 Jan 2012 in PloS one , vol. 7 - pp e38565
Noblanc A , Peltier M, Damon-Soubeyrand C , Kerchkove N, Chabory E, Vernet P, Saez F , Cadet R , Janny L , Pons-Rejraji H , Conrad M, Drevet JR , Kocer A
Liver X receptors, lipids and their reproductive secrets in the male.
Published on 01 Aug 2011 in Biochimica et biophysica acta , vol. 1812 - pp 974-81
El-Hajjaji FZ, Oumeddour A , Pommier AJ, Ouvrier A, Viennois E, Dufour J , Caira F , Drevet JR , Volle DH, Baron S , Saez F , Lobaccaro JM
Dietary cholesterol-induced post-testicular infertility.
Published on 01 Jan 2011 in PloS one , vol. 6 - pp e26966
Ouvrier A, Alves G, Damon-Soubeyrand C , Marceau G , Cadet R , Janny L , Brugnon F , Kocer A , Pommier A, Lobaccaro JM , Drevet JR , Saez F
Glutathione peroxidases at work on epididymal spermatozoa: an example of the dual effect of reactive oxygen species on mammalian male fertilizing ability.
Published on 01 Nov 2011 in Journal of andrology , vol. 32 - pp 641-50
Noblanc A , Kocer A , Chabory E, Vernet P, Saez F , Cadet R , Conrad M, Drevet JR
Liver X receptors, lipids and their reproductive secrets in the male.
Published on 30 Aug 2011 in Biochimica et biophysica acta , vol. 1812 - pp 974-81
El-Hajjaji FZ, Oumeddour A , Pommier AJ, Ouvrier A, Viennois E, Dufour J , Caira F , Drevet JR, Volle DH , Baron S , Saez F , Lobaccaro JM
Epididymis cholesterol homeostasis and sperm fertilizing ability.
Published on 30 Jan 2011 in Asian journal of andrology , vol. 13 - pp 11-7
Deficient tryptophan catabolism along the kynurenine pathway reveals that the epididymis is in a unique tolerogenic state.
Published on 11 Mar 2011 in The Journal of biological chemistry , vol. 286 - pp 8030-8042
Jrad-Lamine A , Henry-Berger J , Gourbeyre P, Damon-Soubeyrand C , Lenoir A , Combaret L, Saez F , Kocer A , Tone S, Fuchs D, Zhu W, Oefner PJ, Munn DH, Mellor AL, Gharbi N, Cadet R , Aitken RJ, Drevet JR
Mammalian glutathione peroxidases control acquisition and maintenance of spermatozoa integrity.
Published on 30 Apr 2010 in Journal of animal science , vol. 88 - pp 1321-31
Chabory E, Damon C, Lenoir A , Henry-Berger J , Vernet P, Cadet R , Saez F , Drevet JR
LXR and ABCA1 control cholesterol homeostasis in the proximal mouse epididymis in a cell-specific manner.
Published on 01 Sep 2009 in Journal of lipid research , vol. 50 - pp 1766-75
Ouvrier A, Cadet R , Vernet P, Laillet B, Chardigny JM, Lobaccaro JM , Drevet JR , Saez F
LXR regulate cholesterol homeostasis in the proximal mouse epididymis.
Published on 01 Jan 2009 in Folia histochemica et cytobiologica , vol. 47 - pp S75-9
Ouvrier A, Cadet R , Lobaccaro JM , Drevet JR , Saez F
[Role of reactive oxygen species (ROS) on human spermatozoa and male infertility].
Published on 30 Jun 2009 in Gynecologie, obstetrique & fertilite , vol. 37 - pp 529-35
Pons-Rejraji H , Sion B, Saez F , Brugnon F , Janny L , Grizard G
Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice.
Published on 30 Jul 2009 in The Journal of clinical investigation , vol. 119 - pp 2074-85
Chabory E, Damon C, Lenoir A , Kauselmann G, Kern H, Zevnik B, Garrel C, Saez F , Cadet R , Henry-Berger J , Schoor M, Gottwald U, Habenicht U, Drevet JR , Vernet P
GPX5, the selenium-independent glutathione peroxidase-encoding single copy gene is differentially expressed in mouse epididymis.
Published on 01 Jan 2008 in Reproduction, fertility, and development , vol. 20 - pp 615-25
Zhang T, Chabory E, Britan A, Grignard E, Pitiot O, Saez F , Cadet R , Henry-Berger J , Vernet P, Drevet JR
Protein composition of human epididymosomes collected during surgical vasectomy reversal: a proteomic and genomic approach.
Published on 30 Aug 2008 in Human reproduction (Oxford, England) , vol. 23 - pp 1698-707
Thimon V, Frenette G, Saez F , Thabet M, Sullivan R
Liver X receptors and epididymal epithelium physiology.
Published on 01 Jul 2007 in Asian journal of andrology , vol. 9 - pp 574-82
Saez F , Chabory E, Cadet R , Vernet P, Baron S , Lobaccaro JM , Drevet JR
Liver X receptors and epididymal epithelium physiology.
Published on 30 Jul 2007 in Asian journal of andrology , vol. 9 - pp 574-82
Saez F , Chabory E, Cadet R , Vernet P, Baron S , Lobaccaro JM , Drevet JR
Identification of sperm antigens as a first step towards the generation of a contraceptive vaccine to decrease fossorial water vole Arvicola terrestris Scherman proliferations.
Published on 15 Sep 2007 in Theriogenology , vol. 68 - pp 779-95
Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
Published on 01 Oct 2004 in Journal of molecular endocrinology , vol. 33 - pp 361-75
Frenoux JM, Vernet P, Volle DH, Britan A, Saez F , Kocer A , Henry-Berger J , Mangelsdorf DJ, Lobaccaro JM , Drevet JR
Nuclear oxysterol receptors, LXRs, are involved in the maintenance of mouse caput epididymidis structure and functions.
Published on 30 Oct 2004 in Journal of molecular endocrinology , vol. 33 - pp 361-75
Frenoux JM, Vernet P, Volle DH , Britan A, Saez F , Kocer A , Henry-Berger J , Mangelsdorf DJ, Lobaccaro JM , Drevet JR
