Angélique DE HAZE
Ingénieur d'étude
DE HAZE
Angélique
Ingénieur d'étude
IE
Publications
LXR pathway drives hormonal response intensity in polycystic ovary syndrome.
Published on 21 May 2025 in EMBO molecular medicine
Dallel S , Despalles M , Tore M , Renaud Y , Kocer A , Damon-Soubeyrand C , Pouchin P , Vachias C , Boutourlinsky K , Gonthier-Gueret C, De Haze A , Sanchez P , Pointud JC , Bouchareb E , Vialat M , Lagarde A , Gulunga C, Chaput L, Vega A , Brugnon F , Tauveron I , Trousson A , de Joussineau C , Degoul F , Morel L , Lobaccaro JM , Maqdasy S , Baron S
Alternative splicing is an FXRα loss-of-function mechanism and impacts energy metabolism in hepatocarcinoma cells.
Published on 01 Jan 2025 in The Journal of biological chemistry , vol. 301 - pp 108022
Garcia M , Holota H , De Haze A , Saru JP , Sanchez P , Battistelli E , Thirouard L , Monrose M , Benoit G, Volle DH , Beaudoin C
Liver X Receptors Enhance Epithelial to Mesenchymal Transition in Metastatic Prostate Cancer Cells.
Published on 06 Aug 2024 in Cancers , vol. 16
Bouchareb E , Dallel S , De Haze A , Damon-Soubeyrand C , Renaud Y , Baabdaty E , Vialat M , Fabre J , Pouchin P , De Joussineau C , Degoul F , Sanmukh S , Gendronneau J , Sanchez P , Gonthier-Gueret C , Trousson A , Morel L , Lobaccaro JM , Kocer A , Baron S
Constitutive Androstane Receptor Regulates Germ Cell Homeostasis, Sperm Quality, and Male Fertility via Akt-Foxo1 Pathway.
Published on 24 Sep 2024 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) - pp e2402082
Monrose M , Holota H , Martinez G, Damon-Soubeyrand C , Thirouard L , Martinot E , Battistelli E , de Haze A , Bravard S , Tamisier C , Caira F , Coutton C, Barbotin AL, Boursier A, Lakhal L, Beaudoin C , Volle DH
Understanding the role of endocrine disrupting chemicals in testicular germ cell cancer: Insights into molecular mechanisms.
Published on 29 Aug 2024 in Molecular aspects of medicine , vol. 99 - pp 101307
Pang WK , Kuznetsova E , Holota H , De Haze A , Beaudoin C , Volle DH
Persistent organic pollutants promote aggressiveness in prostate cancer.
Published on 01 Sep 2023 in Oncogene , vol. 42 - pp 2854-2867
Buñay J, Kossai M, Damon-Soubeyrant C, De Haze A , Saru JP , Trousson A , de Joussineau C , Bouchareb E , Kocer A , Vialat M , Dallel S , Degoul F , Bost F, Clavel S, Penault-Llorca F, Valli MP, Guy L, Matthews J, Renaud Y , Ittmann M, Jones J, Morel L , Lobaccaro JM , Baron S
Identification of a Crosstalk among TGR5, GLIS2, and TP53 Signaling Pathways in the Control of Undifferentiated Germ Cell Homeostasis and Chemoresistance.
Published on 30 Jun 2022 in Advanced science (Weinheim, Baden-Wurttemberg, Germany) , vol. 9 - pp e2200626
Thirouard L , Holota H , Monrose M , Garcia M , de Haze A , Damon-Soubeyrand C, Renaud Y , Saru JP , Perino A, Schoonjans K, Beaudoin C , Volle DH
Identification of the Role of TGR5 in the Regulation of Leydig Cell Homeostasis.
Published on 06 Dec 2022 in International journal of molecular sciences , vol. 23
Holota H , De Haze A , Martinot E , Monrose M , Saru JP , Caira F , Beaudoin C , Volle DH
Analysis of the Reversible Impact of the Chemodrug Busulfan on Mouse Testes.
Published on 13 Sep 2021 in Cells , vol. 10
Thirouard L , Holota H , Monrose M , Garcia M , De Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
New perspectives on PPAR, VDR and FXRα as new actors in testicular pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100886
Monrose M , Thirouard L , Garcia M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Nuclear receptors in physiology and pathophysiology.
Published on 30 Apr 2021 in Molecular aspects of medicine , vol. 78 - pp 100956
Absence of nuclear receptors LXRs impairs immune response to androgen deprivation and leads to prostate neoplasia.
Published on 07 Dec 2020 in PLoS biology , vol. 18 - pp e3000948
Bousset L , Septier A , Bunay J, Voisin A , Guiton R , Damon-Soubeyrant C, Renaud Y , De Haze A , Sapin V , Fogli A , Rambur A , De Joussineau C , Kocer A , Trousson A , Henry-Berger J , Höring M, Liebisch G, Matysik S, Lobaccaro JA, Morel L , Baron S
Farnesoid X receptor alpha (FXRα) is a critical actor of the development and pathologies of the male reproductive system.
Published on 30 Dec 2019 in Cellular and molecular life sciences : CMLS , vol. 76 - pp 4849-4859
Garcia M , Thirouard L , Monrose M , Holota H , De Haze A , Caira F , Beaudoin C , Volle DH
Fxralpha gene is a target gene of hCG signaling pathway and represses hCG induced steroidogenesis.
Published on 30 Nov 2019 in The Journal of steroid biochemistry and molecular biology , vol. 194 - pp 105460
Holota H , Thirouard L , Garcia M , Monrose M , de Haze A , Saru JP , Caira F , Beaudoin C , Volle DH
Individual Comparison of Cholesterol Metabolism in Normal and Tumour Areas in Radical Prostatectomy Specimens from Patients with Prostate Cancer: Results of the CHOMECAP Study.
Published on 30 Mar 2019 in European urology oncology , vol. 2 - pp 198-206
Celhay O , Bousset L , Guy L, Kemeny JL, Leoni V, Caccia C, Trousson A , Damon-Soubeyrant C, De Haze A , Sabourin L, Godfraind C, de Joussineau C , Pereira B, Morel L , Lobaccaro JM , Baron S
Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways.
Published on 15 Nov 2018 in Scientific reports , vol. 8 - pp 16875
Baptissart M , Sèdes L , Holota H , Thirouard L , Martinot E , de Haze A , Rouaisnel B , Caira F , Beaudoin C , Volle DH
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C , De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
Bile acid homeostasis controls CAR signaling pathways in mouse testis through FXRalpha.
Published on 09 Feb 2017 in Scientific reports , vol. 7 - pp 42182
Martinot E , Baptissart M , Véga A , Sèdes L , Rouaisnel B , Vaz F, Saru JP , de Haze A , Baron S , Caira F , Beaudoin C , Volle DH
The Bile Acid Nuclear Receptor FXRα Is a Critical Regulator of Mouse Germ Cell Fate.
Published on 11 Jul 2017 in Stem cell reports , vol. 9 - pp 315-328
Martinot E , Sèdes L , Baptissart M , Holota H , Rouaisnel B , Damon-Soubeyrand C, De Haze A , Saru JP , Thibault-Carpentier C, Keime C, Lobaccaro JA, Baron S , Benoit G, Caira F , Beaudoin C , Volle DH
Bile acid-FXRα pathways regulate male sexual maturation in mice.
Published on 12 Apr 2016 in Oncotarget , vol. 7 - pp 19468-82
Baptissart M , Martinot E , Vega A , Sédes L , Rouaisnel B , de Haze A , Baron S , Schoonjans K, Caira F , Volle DH
Bile Acid Alters Male Mouse Fertility in Metabolic Syndrome Context.
Published on 01 Oct 2015 in PloS one , vol. 10 - pp e0139946
Vega A , Martinot E , Baptissart M , De Haze A , Vaz F, Kulik W, Damon-Soubeyrand C, Baron S , Caira F , Volle DH
Identification of the link between the hypothalamo-pituitary axis and the testicular orphan nuclear receptor NR0B2 in adult male mice.
Published on 02 Mar 2015 in Endocrinology , vol. 156 - pp 660-9
Vega A , Martinot E , Baptissart M , De Haze A , Saru JP , Baron S , Caira F , Schoonjans K, Lobaccaro JM , Volle DH
Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice.
Published on 30 Sep 2014 in Hepatology (Baltimore, Md.) , vol. 60 - pp 1054-65
Baptissart M , Vega A , Martinot E , Pommier AJ, Houten SM, Marceau G , de Haze A , Baron S , Schoonjans K, Lobaccaro JM , Volle DH
Toxicity of copper(I)-NHC complexes against human tumor cells: induction of cell cycle arrest, apoptosis, and DNA cleavage.
Published on 01 Jan 2009 in Chemistry (Weinheim an der Bergstrasse, Germany) , vol. 15 - pp 314-8
Teyssot ML, Jarrousse AS, Chevry A, De Haze A , Beaudoin C , Manin M, Nolan SP, Díez-González S, Morel L , Gautier A
A transgenic mouse line with specific Cre recombinase expression in the adrenal cortex.
Published on 05 Mar 2009 in Molecular and cellular endocrinology , vol. 300 - pp 197-204
Lambert-Langlais S, Val P , Guyot S, Ragazzon B, Sahut-Barnola I , De Haze A , Lefrançois-Martinez AM , Martinez A
